岭南现代临床外科2025,Vol.25Issue(2):112-117,6.DOI:10.3969/j.issn.1009-976X.2025.02.005
腹腔镜胃袖状切除术对肥胖患者甲状腺功能的影响研究
Effect of laparoscopic sleeve gastrectomy on thyroid function in obese patients
任雪康 1李荣振 1朱少功 1夏云展1
作者信息
- 1. 河南中医药大学第五临床医学院(郑州人民医院)普通外科,河南 郑州 450003
- 折叠
摘要
Abstract
Objective To explore the effects of laparoscopic sleeve gastrectomy(LSG)on thyroid function in obese patients and the potential factors affecting thyroid function after surgery.Methods Sixty-seven obese patients who received standardized LSG in Zhengzhou People′s Hospital from October 2019 to October 2021 and completed 1-year follow-up were selected as the study objects.The height,weight,thyroid function indexes(TSH、FT3、FT4),LDL,HDL and other clinical data before and 1 year after LSG were retrospectively collected.The changes of parameters before and after operation were calculated.The related indexes of thyroid function were compared before and 1 year after surgery,and the potential factors affecting the changes of TSH,FT3 and FT4 after surgery were explored.Results TSH level decreased from(2.84±1.60)mIU/L to(1.45±0.71)mIU/L 1 year after surgery(P<0.001).FT3 decreased from(5.51±0.58)pmol/L to(5.16±0.51)pmol/L(P<0.001),and there was no significant difference in FT4 level 1 year after operation.Postoperative BMI(P<0.001)and LDL(P=0.013)were important factors affecting TSH changes.The change of postoperative LDL(P=0.004)was an important factor affecting the change of postoperative FT3.Conclusion LSG has a significant effect on thyroid function in obese patients,and the changes of body mass index(BMI)and LDL are important parameters to predict thyroid function after surgery.关键词
腹腔镜胃袖状切除术/肥胖症/甲状腺功能/代谢综合征Key words
laparoscopic sleeve gastrectomy/obesity/thyroid function/metabolic syndrome分类
临床医学引用本文复制引用
任雪康,李荣振,朱少功,夏云展..腹腔镜胃袖状切除术对肥胖患者甲状腺功能的影响研究[J].岭南现代临床外科,2025,25(2):112-117,6.