岭南现代临床外科2025，Vol.25Issue(2)：135-139,5.DOI:10.3969/j.issn.1009-976X.2025.02.008
神经节苷脂GD2在三阴性乳腺癌中作用的研究进展
Research progress on the role of ganglioside GD2 in triple-negative breast cancer
魏恬恬 1孙祝生1
作者信息
- 1. 新疆医科大学第五附属医院甲乳外科,乌鲁木齐 830011
- 折叠
摘要
Abstract
Triple-negative breast cancer is a subtype of breast cancer with stronginvasiveness and poor prognosis.At the same time,it has found that ganglioside GD2 is abnormally expressed in many malignant tumors.In recent years,the research on GD2 in triple negative breast cancer has made some progress.It was found that GD2 was highly expressed on the surface of triple negative breast cancer cells,which was closely related to the proliferation,invasion and metastasis of tumor cells.GD2 may be a potential therapeutic target for triple negative breast cancer.It is believed that the research around GD2 will open up a new way for the prevention and treatment of triple negative breast cancer.This article reviews the biological characteristics of GD2 and the research progress in triple-negative breast cancer.关键词
三阴性乳腺癌/乳腺肿瘤干细胞/神经节苷脂/GD2/免疫治疗Key words
triple negative breast cancer/breast tumor stem cells/ganglioside/GD2/immuno-therapy分类
临床医学引用本文复制引用
魏恬恬,孙祝生..神经节苷脂GD2在三阴性乳腺癌中作用的研究进展[J].岭南现代临床外科,2025,25(2):135-139,5.
