生态与农村环境学报2025，Vol.41Issue(5)：590-599,10.DOI:10.19741/j.issn.1673-4831.2024.0530
城市入江支流水体中抗生素的源解析与风险评估:以南京金川河为例
Source Apportionment and Risk Assessment of Antibiotics in the Water Bodies of the Nanjing Tributary of the Yangtze River:A Case Study of Jinchuan River
摘要
Abstract
This investigation used solid-phase extraction coupled with ultra performance liquid chromatography-tandem mass spectrometry(SPE-UPLC-MS/MS)to analyze antibiotic pollution patterns in the Jinchuan River,a tributary of the Yangtze River in Nanjing.By quantified five major antibiotic classes-quinolones,macrolides,sulfonamides,tetracyclines,and penicillins-in surface water to identify the pollution sources and assess the ecological risks.Results show that the anti-biotic concentrations ranging from n.d.to 273.06 ng·L-1,with a mean concentration of 229.37 ng·L-1.Comparative a-nalysis revealed significantly elevated antibiotic levels in the Jinchuan River relative to the level in the main Yangtze River channel.Source apportionment modeling identified four primary contamination sources:the effluents of municipal sewage treatment plants constituted the predominant sourc(48.5％),followed by non-centralized domestic wastewater discharges(29.2％),aquaculture wastewater(15.5％),and pharmaceutical manufacturing effluents(6.8％).Ecological risk as-sessment using risk quotients(RQ)indicated elevated concerns for enoxacin,roxithromycin,and clarithromycin(RQ＞0.1),whereas other detected antibiotics exhibited minimal ecological impact(RQ＜0.1).Additionally,most antibiotics posed a low risk for developing resistance.These findings provide a scientific foundation for targeted antibiotic pollution control and risk management strategies.关键词
抗生素/金川河/入江支流/源解析/风险评估Key words
antibiotics/Jinchuan River/tributaries of the Yangtze River/source apportionment/risk assessment分类
环境科学引用本文复制引用
唐娜,康国栋,鲁磊磊,谭韵洲,陈苹,张圣虎,许晶晶,漆丹..城市入江支流水体中抗生素的源解析与风险评估:以南京金川河为例[J].生态与农村环境学报,2025,41(5):590-599,10.基金项目
南通市科技项目(MS22022108) （MS22022108）
江苏省卓越博士后计划(2024ZB799) （2024ZB799）
