山西中医药大学学报2025，Vol.26Issue(3)：254-258,275,6.DOI:10.19763/j.cnki.2096-7403.2025.03.04
《常见病医方、医案、医论系列丛书·失眠症中医诊疗经验集》治疗失眠的用药规律研究
Research on the medication rules of Chang Jian Bing Yi Fang,Yi An,Yi Lun Xi Lie Cong Shu·Shi Mian Zheng Zhong Yi Zhen Liao Jing Yan Ji in the treatment of insomnia
摘要
Abstract
Objective:To analyze the medication rules of traditional Chinese medicine in the treatment of insomnia,so as to provide reference for its clinical treatment.Methods:Clinical cases for the treatment of insomnia that met the crite-ria in Chang Jian Bing Yi Fang,Yi An,Yi Lun Xi Lie Cong Shu·Shi Mian Zheng Zhong Yi Zhen Liao Jing Yan Ji were screened.The Chinese herbal prescriptions were extracted,the names of the Chinese herbal medicines were standardized and the data were entered.The database was established using Microsoft Excel 2021 software.IBM SPSS Statistics26.0 and Modeler 18.0 software were used to calculate the frequency of drugs,properties,flavors,channel tropism and categories in the prescriptions,and cluster analysis and association rule analysis were performed on high-frequency drugs.Results:There were 83 prescriptions for insomnia contained in Chang Jian Bing Yi Fang,Yi An,Yi Lun Xi Lie Cong Shu·Shi Mian Zheng Zhong Yi Zhen Liao Jing Yan Ji,involving 171 Chinese herbs.The properties were mainly warm,cold and mild.The flavors were mainly sweet,bitter and pungent.The Chinese herbs mainly entered the liver and spleen meridians.There were 18 drugs used more than 20 times,and the top 5 drugs were Suanzaoren,Chaihu,Shouwuteng,Longgu and Danggui.The drugs were divided into 5 categories by cluster analysis.The C1 was Longgu,Muli,Fuling and Gancao;the C2 was Shou-wuteng,Yujin,Hehuanpi,Chaihu and Zhiqiao;the C3 was Danggui,Shengdihuang,Suanzaoren and Boziren;the C4 was Baishao,Zhigancao,Danshen and Yuanzhi;the C5 was Huanglian.Shouwuteng-Suanzaoren was the couplet medicines with the highest support in the second-order association rule,and Chaihu+Shouwuteng-Suanzaoren was the drug combina-tion with the highest support in the third-order drug association rules.Conclusion:Modern medical doctors are good at treating insomnia from the perspectives of liver-spleen co-regulation and regulating and harmonizing Qi and blood.Most of them take mostly by benefiting Qi and blood,dredging the liver and relieving depression,strengthening the spleen and har-monizing the middle energizer as the treatment principles,aiming to promote the functional balance of viscera,regulate the body's Yin and Yang.The harmony of Yin and Yang means the insomnia will be at ease,which is in line with the systematic thinking of treating both symptoms and root causes and the whole regulation in traditional Chinese medicine.关键词
失眠症/数据挖掘/用药规律/关联规则/聚类分析Key words
insomnia/data mining/medication rules/association rules/clustering analysis分类
医药卫生引用本文复制引用
王名望,高丽丽..《常见病医方、医案、医论系列丛书·失眠症中医诊疗经验集》治疗失眠的用药规律研究[J].山西中医药大学学报,2025,26(3):254-258,275,6.基金项目
福建省卫健委医学创新课题(2022CXA052) （2022CXA052）
福建中医药大学重大科技创新"揭榜挂帅"专项项目(XJB2022003-3) （XJB2022003-3）
