有色金属材料与工程2025，Vol.46Issue(2)：35-42,8.DOI:10.13258/j.cnki.nmme.20240312006
TiO2-HA(掺杂Zn2+)复合涂层的制备及其生物学性能研究
Preparation and biological performance study of TiO2-HA(doped with Zn2+)composite coating
摘要
Abstract
Hydroxyapatite(HA)coating has been widely used as the surface coating for metal implants due to its good biocompatibility and bioactivity.However,the HA coating has a low bond strength to the titanium alloy matrix and the HA coating tends to flake off after implantation,leading to a decrease in corrosion resistance,and its antibacterial properties need to be improved.To enhance the bond strength,corrosion resistance,and antimicrobial properties of the HA coating,the surface of Ti6Al4V was respectively subjected to acid etching,alkali heat treatment,and alkali heat treatment after acid etching.Subsequently,TiO2-HA(doped with Zn2+)composite coatings were prepared using the sol-gel method.The results indicate that TiO2-HA(doped with Zn2+)composites were successfully synthesized by the sol-gel method.After alkali heat treatment,the cracks in the HA coating of Ti6Al4V were reduced,and its surface wettability and corrosion resistance were improved.The addition of TiO2 and Zn2+increases the integrity of the HA coating,improving the corrosion resistance and wettability.Staphylococcus aureus(S.aureus)and Escherichia coli(E.coli)reached 69.3％and 96.9％,respectively,indicating an improvement in antibacterial properties.关键词
复合涂层/表面改性/抗腐蚀性/抑菌性能Key words
composite coating/surface modification/corrosion resistance/antimicrobial properties分类
金属材料引用本文复制引用
车贤东,马凤仓,李伟,陈小红,刘新宽,张柯..TiO2-HA(掺杂Zn2+)复合涂层的制备及其生物学性能研究[J].有色金属材料与工程,2025,46(2):35-42,8.基金项目
国家自然科学基金资助项目(51771119) （51771119）
上海市自然科学基金资助项目(17ZR1419600) （17ZR1419600）
