色谱2025，Vol.43Issue(6)：594-605,12.DOI:10.3724/SP.J.1123.2024.05032
有序多孔材料在色谱分离分析领域的应用
Applications of ordered porous materials in chromatography separation and analysis
摘要
Abstract
Chromatography,a highly efficient and selective separation technology,is broadly applicable and exhibits a range of developmental prospects.The stationary phase of a chroma-tography column is the most important component of chromatography;hence,the development of advanced stationary-phase materials that exhibit highly resolved separation performance is a continuing research hotspot in this field.In this regard,ordered porous materials(OPMs)are advantageous owing to their precisely controllable pore sizes,morphologies,and regularly arranged pore structures,which are capable of accurately sieving molecules of different sizes and shapes,and reducing disordered molecular diffusion in the flow path.Such materials overcome the limitation of separation accuracy of traditional chromatographic materials,and effectively solve the problems faced by scientific research and industry in the purification of raw materials and products.Over the past few decades,a variety of new OPMs have been developed and used as stationary-phase matrices in chromatography columns.These materials have efficiently and rapidly separated homologues,isomers,isotopes,and other substances with similar properties,and have delivered excellent chromatographic separation and analysis results.In this review,we first discuss the influence of ordered porous structures on column efficiency and resolution during chromatographic separation from a theoretical perspective,which provides a basis for the use of OPMs as stationary phases in chromatography.This review then summarizes research progress on several different OPM types for use in chromatographic separation and analysis applications,including metal organic frameworks(MOFs),covalent organic frameworks(COFs),porous organic cages(POCs),mesoporous silica materials,block copolymer(BCP)assemblies,and high internal-phase emulsion polymers(PolyHIPEs).The review concludes by discussing current challenges faced by chromatographic OPMs as well as directions for future development.关键词
有序多孔材料/色谱分离分析/框架材料/自组装/聚合物/综述Key words
ordered porous materials(OPMs)/chromatography separation and analysis/framework materials/self-assembly/polymer/review分类
化学引用本文复制引用
王朝旭,王端达,王树涛,宋永杨..有序多孔材料在色谱分离分析领域的应用[J].色谱,2025,43(6):594-605,12.基金项目
国家重点研发计划(2022YFA1206900). National Key R&D Program of China(No.2022YFA1206900). （2022YFA1206900）
