山西大学学报（自然科学版）2025，Vol.48Issue(3)：578-588,后插1-后插5,封3,17.DOI:10.13451/j.sxu.ns.2024167
B、N和F共掺杂的新型碳点对硝唑类抗生素的检测
A Novel Multifunctional Probe Based on Carbon Dots Co-doped B,N and F for Detection of Nitroimidazole Antibiotics
摘要
Abstract
Blue fluorescent carbon dots(BNF-CDs)co-doped with boron,nitrogen and fluorine were prepared by a one-step solvo-thermal method using sodium fluoroborate,citric acid,ethylamine and acetonitrile as precursors.Herein,the structure,morphology and optical properties of BNF-CDs were characterized by transmission electron microscopy,Fourier transform infrared spectrometer,X-ray photoelectron spectroscopy,UV-Vis absorption and fluorescence spectroscopy,respectively.The results illustrated that the BNF-CDs have stable and excellent optical properties with a high fluorescence quantum yield of 65.9%.Based on the internal filtra-tion effect between BNF-CDs and nitroimidazole antibiotics,the fluorescence of BNF-CDs can be effectively quenched.This phe-nomenon provides a novel fluorescence method for the determination of metronidazole(MTR),ornidazole(ORN)and tinidazole(TIN),and the corresponding detection curves for these nitroimidazole antibiotics were established,with linear ranges of 6-250 μmol/L for MTR,3.6-189 μmol/L for ORN and 3.6-295 μmol/L for TIN.The detection limits were found to be 16 nmol/L,35 nmol/L and 71 nmol/L,respectively.In addition,satisfactory recovery rates(rangihg from 96.4%to 105.8%)have been achieved for determination of MTR,ORN and TIN in actual samples,which indicates its potential application in the future.关键词
硝唑类抗生素/碳点/内滤效应/多功能检测Key words
nitroimidazole antibiotics/carbon dots/internal filtration effect/multifunctional detection分类
化学化工引用本文复制引用
贾燕春,胡军辉,宋胜梅,双少敏,董川..B、N和F共掺杂的新型碳点对硝唑类抗生素的检测[J].山西大学学报（自然科学版）,2025,48(3):578-588,后插1-后插5,封3,17.基金项目
国家自然科学基金(22274090) （22274090）
山西省经方扶阳重点实验室(202104010910011) （202104010910011）
山西省基础研究项目(202203021221026) （202203021221026）
山西省专利转化项目(202306012) （202306012）
