护理研究2025，Vol.39Issue(10)：1608-1612,5.DOI:10.12102/j.issn.1009-6493.2025.10.004
维持性血液透析病人中重度瘙痒发生现状及影响因素
Status quo and influencing factors of moderate to severe pruritus in patients with maintenance hemodialysis
摘要
Abstract
Objective:To investigate status quo of moderate to severe pruritus in patients with maintenance hemodialysis,analyze its influencing factors and develop predictive models.Methods:A total of 155 patients with maintenance hemodialysis admitted to The Second Affiliated Hospital of Army Medical University were selected as subjects from February 2020 to June 2023.General information and disease-related information of patients were collected,and pruritus severity of patients was assessed.Results:Among 155 patients with maintenance hemodialysis,42 patients experienced moderate to severe pruritus,with an incidence rate of 27.10%.The results of Logistic regression analysis showed that dry skin,iPTH levels,concurrent anemia,Kt/V,and serum phosphorus were influencing factors of moderate to severe pruritus in patients with maintenance hemodialysis(P<0.05).A Logistic regression model and a decision tree model were developed to predict moderate to severe pruritus.The area under the curve(AUC)of receiver operator characteristic of decision tree model was 0.936(95%CI 0.885-0.969),while the AUC of Logistic regression model was 0.901(95%CI 0.842-0.943).The decision tree model demonstrated a significantly higher AUC than the Logistic regression model(Z=1.979,P=0.049).Conclusions:Dry skin,iPTH levels,concurrent anemia,Kt/V,and serum phosphorus have effect on moderate to severe pruritus in patients with maintenance hemodialysis.The decision tree model exhibits superior predictive efficacy for moderate to severe pruritus in patients with maintenance hemodialysis.关键词
维持性血液透析/瘙痒/影响因素/回归模型/决策树模型Key words
maintenance hemodialysis/pruritus/influencing factors/regression model/decision tree model引用本文复制引用
熊周,张雨婷,柏晓鑫,谭思雨,杨瑾宇..维持性血液透析病人中重度瘙痒发生现状及影响因素[J].护理研究,2025,39(10):1608-1612,5.基金项目
中国人民解放军陆军军医大学第二附属医院护理培育项目,编号:2024-HLPY-13 （）
