实用医学杂志2025，Vol.41Issue(10)：1597-1602,6.DOI:10.3969/j.issn.1006-5725.2025.10.024
丹皮酚治疗肠道疾病作用机制研究进展
Research progress on mechanism of paeonol in the treatment of intestinal diseases
摘要
Abstract
As the lifestyle of modern people changes,genetic factors continue to become more prominent,and the impact of environmental and water pollution,the incidence of intestinal diseases(colorectal cancer,inflammatory bowel disease,irritable bowel syndrome,chronic constipation,etc.)is increasing.It not only seriously endangers the health of the population,but also consumes a large amount of medical resources.Paeonol,as a class of small molecule phenolic compounds,has a wide range of biological activities,such as anti-inflammatory,anti-viral,anti-tumor,anti-allergic,immune regulation,cardiovascular and cerebrovascular protection,etc.The mechanism and experimental research on the effect of paeonol in preventing and treating intestinal diseases based on the"Brain-Gut-Bacteria axis"are also in-depth.This article aims to systematically review and sort out the latest progress in this field,with a view to providing certain ideas and methods for the precise treatment of intestinal diseases and the development of new drugs.关键词
丹皮酚/肠道疾病/作用机制/研究进展Key words
paeonol/intestinal diseases/mechanism in the treatment/research progress分类
临床医学引用本文复制引用
王伟,路士华,张宏昊,邓华亮..丹皮酚治疗肠道疾病作用机制研究进展[J].实用医学杂志,2025,41(10):1597-1602,6.基金项目
国家自然科学基金项目(编号:81904128) （编号:81904128）
国家中医药管理局科技司共建科技项目(编号:GZY-KJS-SD-2023-035) （编号:GZY-KJS-SD-2023-035）
山东省中医药科技项目(编号:面上项目M-2023167) （编号:面上项目M-2023167）
山东省中医药疗效机理重点实验室项目(编号:PKL2024C23) （编号:PKL2024C23）
山东省中医药重点学科中医脾胃病学项目(编号:鲁卫中医药科教字[2022]4号) （编号:鲁卫中医药科教字[2022]4号）
