生殖医学杂志2025，Vol.34Issue(5)：571-579,9.DOI:10.3969/j.issn.1004-3845.2025.05.001
中华医学会生殖医学分会:2017-2021年辅助生殖技术数据报告
A summary of the annual report on assisted reproductive technology of Chinese Society of Reproductive Medicine between 2017 and 2021
摘要
Abstract
Objective:The report concerning the application and safety of assisted reproductive technology(ART)in China from 2017 to 2021 were summarized,in order to assess its clinical outcomes and to provide a scientific basis for future research and policy-making. Methods:The data for this study were obtained from the Chinese Society of Reproductive Medicine(CSRM)Data Reporting System that covered the key outcomes of ART. Results:Up to September 25,2023,the CSRM Data Reporting System had received the ART data from 257,293,262,230 and 194 reproductive medicine centers in 2017,2018,2019,2020 and 2021,respectively.The conventional IVF/ICSI cycles were mainly applied in women under 35 years old,accounting for 65.53％,64.21％,67.86％,69.30％and 67.10％between 2017 and 2021,respectively.The rate of single embryo transfer in controlled ovarian stimulation(COS)cycles had increased year by year,accounting for 18.64％,25.73％,32.90％,36.09％and 39.61％between 2017 and 2021,respectively.The rate of multiple pregnancies in fresh embryo transfer cycles among individuals under the age of 35 had been declining year by year.However,the rate of multiple pregnancies among individuals under the age of 35 remained obviously higher than that of women aged 35 years and above.There was no significant change concerning the clinical pregnancy rates of conventional IVF cycles from 2017 to 2021 for people under 35 years old(58.23％to 59.06％,P＞0.05),while the live birth rates remained the same in 2017,2020 and 2021,which were significantly higher than those in 2018 and 2019(48.26％to 50.16％,P＜0.05).The clinical pregnancy rates and live birth rates for people aged 35 years and above were significantly higher in 2018 and 2021 than those in 2017,2019 and 2020,ranging from 39.65％to 42.53％and 28.69％to 31.45％,respectively(P＜0.05).The clinical pregnancy rate and live birth rate in ICSI cycles for people under 35 years old ranged from 53.67％to 56.08％and from 45.84％to 47.90％,respectively.The clinical pregnancy rate for women aged 35 years and above ranged from 35.87％to 37.62％,and the live birth rate ranged from 25.98％to 27.11％.The clinical pregnancy rate and live birth rate in FET cycles showed an upward trend,ranging from 48.98％to 53.95％and from 37.98％to 43.05％,respectively.The multiple pregnancy rate was declining year by year,from 19.26％to 27.85％.From 2017 to 2021,the incidence of birth defects after undergoing assisted reproduction was controlled under 1％.While the incidence of moderate to severe OHSS was controlled,ranging from 1.06％to 1.58％,and the incidence of postoperative bleeding(＞300 ml),postoperative pelvic infection and other complications all ranged from 0.01％to 0.20％. Conclusions:The ART clinical pregnancy rate and live birth rate increased slightly from 2017 to 2021.The multiple pregnancies rate and the incidence of birth defects decreased,and the complications were effectively controlled.However,the multiple pregnancies rate was still at a high level,especially among people under 35 years old.A sustained efforts are needed to reduce the multiple pregnancies rate in the future.关键词
辅助生殖技术/中华医学会生殖医学分会/年度报告Key words
Assisted reproductive technology/Chinese society of reproductive medicine/Annual report分类
临床医学引用本文复制引用
郭小妮,沈浣,师娟子,滕晓明,王晓红,王秀霞,伍琼芳,曾勇,张松英,钟影,孙莹璞,邓成艳,孙海翔,黄国宁,黄学锋,刘平,周灿权,冯云,郝桂敏,卢文红,全松..中华医学会生殖医学分会:2017-2021年辅助生殖技术数据报告[J].生殖医学杂志,2025,34(5):571-579,9.基金项目
国家自然科学基金(82371728) （82371728）
重庆市技术创新与应用发展专项(CSTB2022TIAD-KPX0146) （CSTB2022TIAD-KPX0146）
