摘要
Abstract
Objective To explore the application effect of ultrasound-guided thoracic paravertebral nerve block combined with general anesthesia in radical mastectomy for breast cancer.Methods A total of 80 patients undergoing radical mastectomy for breast cancer admitted to Dingzhou People's Hospital from May 2022 to June 2024 were selected and divided into two groups using the random number table method,with 40 cases in each group.The control group received tracheal intubation for general anesthesia,while the observation group received ultrasound-guided thoracic paravertebral nerve block before anesthesia induction on the basis of the control group.The intraoperative anesthetic maintenance drug dosage,postoperative 12 hours pain score and serum substance P(SP)level,anesthesia recovery indicators,and incidence of adverse reactions or complications were compared between the two groups.Results The intraoperative dosage of Sufentanil,Ciprofol,and Remifentanil in the observation group was less than that in the control group(P<0.05).The observation group had lower postoperative 12 hours pain score and serum SP level than the control group(P<0.05).The time of postoperative eye opening,extubation,and resuscitation room stay in the observation group was shorter than that in the control group(P<0.05).The total incidence of intraoperative hypertension,intraoperative awareness,delayed postoperative awakening,and severe postoperative pain in the observation group was lower than that in the control group(P<0.05).Conclusion Ultrasound-guided thoracic paravertebral nerve block combined with general anesthesia can reduce the dosage of intraoperative anesthetic drugs during radical mastectomy for breast cancer,reduce the pain level,promote postoperative recovery,and reduce adverse reactions and complications.关键词
超声引导/胸椎旁神经阻滞/全身麻醉/乳腺癌根治术Key words
Ultrasound-guided/Thoracic paravertebral nerve block/General anesthesia/Radical mastectomy for breast cancer分类
医药卫生
