微创医学2025，Vol.20Issue(1)：58-61,4.DOI:10.11864/j.issn.1673.2025.01.10
CT造影检查中不同造影剂浓度及辐射剂量方案诊断泌尿系统疾病的效果分析
Effectiveness evaluation of different contrast medium concentrations and radiation doses on the diagnosis of urinary system diseases in CT angiography
摘要
Abstract
Objective To make an effectiveness evaluation of different contrast medium concentrations and dosage regimens on the diagnosis of urinary system diseases in CT angiography.Methods A total of 90 patients who underwent CT urography at at Nanning Red Cross Hospital from January 2020 to January 2021 were selected as the research subjects.Among them,45 patients who received CT angiography with the conventional contrast medium concentration and dosage were set as the control group.At the same time,45 patients who received CT angiography with the optimized contrast medium concentration and dosage regimen and whose general data were comparable to those of the control group were set as the observation group.The contrast-to-noise ratio(CNR)of the bilateral kidneys,ureters,and bladders,as well as the serum creatinine levels and other relevant indicators,were compared between the two groups.Results There was no statistically significant difference in the contrast image effects between the two groups(P>0.05).No statistically significant difference was observed in the CNR of the bilateral kidneys and ureters between the two groups(all P>0.05).However,the CNR at the bladder level in the observation group was significantly higher than that in the control group,with a statistically significant difference(P<0.05).The volume of contrast agent administered to the observation group was(44.00±3.81)mL,while that for the control group was(66.03±3.51)mL,with a statistically significant difference between the two groups(P<0.05).Before angiography,the serum creatinine levels of the two groups showed no statistically significant difference(P>0.05).After angiography,although the serum creatinine levels increased in both groups,the level in the observation group was significantly lower than that in the control group,with a statistically significant difference(P<0.05).After angiography,acute renal injury occurred in 2 cases(4.44%)of the observation group and 10 cases(22.22%)of the control group,the difference between the two groups was statistically significant(P<0.05).Conclusion Contrast agents administered at low doses and concentrations can generate images with quality equivalent to that of the conventional concentration-dosage regimen,and has the advantages of higher safety,which can effectively reduce the incidence of acute renal injury,and is worthy of clinical application and promotion.关键词
尿路造影术/CT造影/辐射剂量/造影剂/浓度/泌尿系疾病/诊断Key words
Urography/CT angiography/Radiation dose/Contrast media/Concentration/Urinary system diseases/Diagnosis引用本文复制引用
李伟频,吴琮宁,李博峰..CT造影检查中不同造影剂浓度及辐射剂量方案诊断泌尿系统疾病的效果分析[J].微创医学,2025,20(1):58-61,4.基金项目
广西壮族自治区卫生健康委员会自筹经费科研课题(编号:Z20200971) （编号:Z20200971）
