局解手术学杂志2025，Vol.34Issue(5)：405-408,4.DOI:10.11659/jjssx.11E024061
垂体瘤术后发生尿崩症的影响因素分析
Analysis of influencing factors of diabetes insipidus after pituitary tumor surgery
摘要
Abstract
Objective To analyze the influencing factors of diabetes insipidus after pituitary tumor surgery,thereby providing evidence for enhancing perioperative management of pituitary tumor surgery and preventing diabetes insipidus after pituitary tumor surgery.Methods The clinical data of patients who underwent pituitary tumor surgery in our hospital from January 2014 to December 2024 were retrospectively analyzed.The relationship between each variable and postoperative diabetes insipidus was explored through univariate analysis,and multi-variate regression analysis was used to identify the independent risk factors for the occurrence of postoperative diabetes insipidus.Results Univariate analysis showed that the occurrence of diabetes insipidus after pituitary tumor surgery was related to tumor invasiveness,tumor growth direction,surgical resection degree,surgical time and surgical method(P<0.05).Logistic regression analysis showed that the surgical time>4 hours(P=0.001)and tumor growth breaking through diaphragma sellae(P=0.004)were independent risk factors for the occurrence of postoperative diabetes insipidus.Conclusion The surgical time and tumor growth direction are closely related to diabetes insipidus after pituitary tumor surgery;therefore,in order to reduce the incidence of diabetes insipidus after pituitary tumor surgery,a thorough evaluation should be conducted preoperatively to clarify the direction of tumor growth;minimally invasive surgery should be adopted as much as possible during the operation and the skills of surgeons should be improved to shorten the surgical time;and close observation should performed after surgery.关键词
垂体瘤/尿崩症/经蝶手术/危险因素/术后管理Key words
pituitary tumor/diabetes insipidus/transphenoidal surgery/risk factors/postoperative management分类
临床医学引用本文复制引用
何茂林,周昌龙..垂体瘤术后发生尿崩症的影响因素分析[J].局解手术学杂志,2025,34(5):405-408,4.基金项目
永川区自然科学基金计划项目(2022yc-jckx20021) （2022yc-jckx20021）
