中国康复理论与实践2025，Vol.31Issue(5)：497-504,8.DOI:10.3969/j.issn.1006-9771.2025.05.001
高压氧舱内同步脑仿生电刺激对脑卒中相关睡眠障碍的效果
Effect of synchronous brain bionic electrical stimulation in hyperbaric oxygen chamber on stroke-related sleep disorders
摘要
Abstract
Objective To explore the effect of hyperbaric oxygen combined with synchronous brain bionic electrical stimulation on patients with stroke-related sleep disorders. Methods From November,2023 to November,2024,a total of 68 stroke patients with stroke-related sleep disorders ad-mitted to Huashan Hospital,Fudan University were selected.They were randomly divided into control group(n=34)and experimental group(n=34).The control group received routine hyperbaric oxygen therapy,while the ex-perimental group received routine hyperbaric oxygen therapy combined with synchronous brain bionic electrical stimulation inside the chamber,for four weeks.Pittsburgh Sleep Quality Index(PSQI),sleep-monitoring wrist-bands,Self-rating Anxiety Scale(SAS)and Self-rating Depression Scale(SDS)were used to assess the outcomes before and after treatment.. Results Four patients in the control group and one in the experimental group dropped out.After treatment,the scores of each factors of PSQI decreased in both groups(t>2.693,P<0.05),and were lower in the experimental group than in the control group(t>2.699,P<0.01),expect hypnotic drug use(P>0.05);the total sleep time,deep sleep time and rapid eye movement sleep time became longer in both groups(|t|>7.270,P<0.001),and they were longer in the experimental group than in the control group(|t|>5.712,P<0.001);the scores of SAS and SDS decreased in both groups(t>9.530,P<0.001),and they were less in the experimental group than in the control group(t>4.740,P<0.001). Conclusion Synchronous brain bionic electrical stimulation in hyperbaric oxygen chamber could effectively prolong the total sleep time,deep sleep time and rapid eye movement time of patients with stroke-related sleep disorders,re-lieve anxiety and depression after stroke,and improve sleep quality.关键词
脑卒中/睡眠障碍/高压氧治疗/同步脑仿生电刺激/情绪障碍Key words
stroke/sleep disorders/hyperbaric oxygen therapy/synchronized brain bionic electrical stimulation/emotional disorders分类
临床医学引用本文复制引用
梁丹,王卫宁,李策,吴越,徐舒,谢鸿宇,吴毅,朱玉连..高压氧舱内同步脑仿生电刺激对脑卒中相关睡眠障碍的效果[J].中国康复理论与实践,2025,31(5):497-504,8.基金项目
1.国家自然科学基金青年项目(No.82102666) （No.82102666）
2.上海市科技创新行动计划医学创新研究专项(No.22Y31900202) （No.22Y31900202）
3.上海市创新医疗器械应用示范项目(No.23SHS05400-05) Supported by National Natural Science Foundation of China(Youth)(No.82102666),Shanghai Science and Technology Innovation Action Plan Medical Innovation Research Special Project(No.22Y31900202),and Shanghai Innovative Medical Device Application Demonstration Project(No.23SHS05400-05) （No.23SHS05400-05）
