中国康复理论与实践2025,Vol.31Issue(5):513-519,7.DOI:10.3969/j.issn.1006-9771.2025.05.003
耳迷走神经电刺激联合双任务训练对缺血性脑卒中患者上肢功能的效果
Effect of transcutaneous auricular vagus nerve stimulation combined with dual-task training on upper limb func-tion in patients with ischemic stroke
摘要
Abstract
Objective To explore the effect of transcutaneous auricular vagus nerve stimulation(taVNS)combined with dual-task training(DTT)on upper limb function recovery in patients with ischemic stroke. Methods From January to October,2024,60 ischemic stroke patients with upper limb dysfunction admitted to Zhejiang Rehabilitation Medical Center were selected and randomly divided into control group(n=30)and observation group(n=30).Both groups received conventional rehabilitation training.The control group underwent sham-taVNS combined with DTT,while the observation group received active taVNS combined with DTT,for four weeks.Before and after treatment,they were assessed with Fugl-Meyer Assessment-Upper Extremities(FMA-UE),Action Research Arm Test(ARAT),modified Barthel Index(MBI)and motor-evoked potential(MEP)tests. Results The FMA-UE scores,ARAT scores,MBI scores,MEP amplitude and MEP latency improved in both groups af-ter treatment(|t|>3.670,P<0.01),and were superior in the observation group than in the control group(|t|>3.081,P<0.01). Conclusion The combination of taVNS and DTT can significantly improve upper limb function,enhance activities of daily living,and promote neurological recovery in patients with ischemic stroke.关键词
缺血性脑卒中/上肢/功能障碍/耳迷走神经电刺激/双任务训练/运动诱发电位Key words
ischemic stroke/upper limb/dysfunction/transcutaneous auricular vagus nerve stimulation/dual-task training/motor-evoked potential分类
临床医学引用本文复制引用
邹聪聪,王潇珺,马锦蓉,鲁商波,丁勇,王哈妮,宋建飞..耳迷走神经电刺激联合双任务训练对缺血性脑卒中患者上肢功能的效果[J].中国康复理论与实践,2025,31(5):513-519,7.基金项目
1.浙江省中医药科技计划项目(No.2024ZL769) (No.2024ZL769)
2.浙江省康复医学会科研专项基金项目(No.ZKKY2023011) (No.ZKKY2023011)
3.浙江康复医疗中心院级科研课题(No.ZKYJ2312) Supported by Zhejiang Province Traditional Chinese Medicine Science and Technology Project(No.2024ZL769),Zhejiang Rehabilitation Medical Association Research Fund Project(No.ZKKY2023011),and Zhejiang Rehabilitation Medical Center Institutional Research Project(No.ZKYJ2312) (No.ZKYJ2312)