中国输血杂志2025，Vol.38Issue(5)：637-643,7.DOI:10.13303/j.cjbt.issn.1004-549x.2025.05.007
CD36介导的免疫反应与输血安全
CD36-mediated immune response and transfusion safety
摘要
Abstract
Cluster of differentiation 36(CD36)is a highly glycosylated double transmembrane glycoprotein,which is involved in the inflammatory response and immune regulation of the body.It plays a key role in mediating the mechanism of immune-related blood transfusion reactions and regulating the function of immune cells.It has an important impact on blood transfusion safety and has become a current research hotspot.This article reviews and comprehensively analyzes the research progress of the specific role of CD36 in the immune response of blood transfusion and its regulatory mechanism at home and abroad.Combined with clinical cases and experimental data,the pathophysiological mechanism of CD36 in immune re-sponse and its immune-mediated blood transfusion safety issues are reviewed.It is expected to provide new theoretical sup-port and practical guidance for the field of blood transfusion safety and promote the further development of blood transfusion medicine.关键词
CD36/免疫反应/输血相关免疫调节/输血安全/输血策略Key words
CD36/immune response/transfusion-related immunomodulation/transfusion safety/blood transfusion strategy分类
临床医学引用本文复制引用
揭小梅,何子毅,胡应明,贝孟辉..CD36介导的免疫反应与输血安全[J].中国输血杂志,2025,38(5):637-643,7.基金项目
东莞市社会科技发展重点项目(20231800936012) （20231800936012）
