中国输血杂志2025，Vol.38Issue(5)：684-690,7.DOI:10.13303/j.cjbt.issn.1004-549x.2025.05.014
麻醉监护下贮存式自体输血技术的临床应用
Clinical application of preoperative autologous blood donation under anesthesia monitoring
摘要
Abstract
Objective To evaluate the safety and efficacy of preoperative autologous blood donation(PABD)under an-esthesia monitoring in elective surgical procedures,and to provide scientific data for promoting its clinical application.Methods 1)A total of 1 164 patients scheduled for elective surgery and met the criteria for stored autologous blood trans-fusion in our hospital from March 2022 to September 2023 were enrolled.Prior to surgery,stored autotransfusion was per-formed under anesthesia monitoring.During the operation,blood pressure(BP),heart rate(HR),blood oxygen saturation(SpO2)and other basic life indicators before and after blood collection were recorded and analyzed.Adverse reactions dur-ing blood collection were documented,and potential influencing factors were analyzed.2)The autologous transfusion group(experimental group,patients receiving intraoperative autologous blood reinfusion)was compared with the allogeneic trans-fusion group(control group,patients without PABD during the same period)using propensity score matching.The length of hospital stay,transfusion-related costs,perioperative hemoglobin(Hb),hematocrit(Hct),platelet count(Plt)and coag-ulation function were compared between the two groups after matching.Results 1)Three patients(0.26%)had adverse reactions during blood collection.Autologous blood transfusion was performed in 443 patients(38.1%)during or after oper-ation,with no adverse reaction during blood transfusion.2)The systolic blood pressure(SBP)and diastolic blood pressure(DBP)of patients after blood collection were lower than before blood collection,and the SpO2 was higher than before blood collection,with statistically significant differences(P<0.05);There was no significant difference in heart rate before and after blood collection(P>0.05);Our analysis found that age,gender,blood collection volume,department,or mild-to-moderate circulatory system complications didn't significantly affect BP,HR and SpO2 fluctuations(P>0.05).3)The ex-perimental group had shorter hospital stays and lower transfusion costs than the control group(P<0.05).4)No significant differences were observed in Hb,Hct,Plt levels or coagulation function(PT,APTT)between the two groups after opera-tion(P>0.05).The hospitalization duration and transfusion related expenses in the experimental group were lower than those in the control group(P<0.05).Conclusion PABD under anesthesia monitoring is safe and feasible in elective sur-geries across diverse patient groups and surgical fields.It reduces the costs and conserves blood resources,which is worthy of further promotion.关键词
贮存式自体输血/麻醉监护/外科择期手术Key words
preoperative autologous blood donation(PABD)/anesthesia monitoring/elective surgery分类
医药卫生引用本文复制引用
杜春红,史永久,隋委伽,周令怡,张新歌..麻醉监护下贮存式自体输血技术的临床应用[J].中国输血杂志,2025,38(5):684-690,7.基金项目
天津医科大学总医院扬帆项目(22TSC040) （22TSC040）
