中国输血杂志2025，Vol.38Issue(5)：704-710,7.DOI:10.13303/j.cjbt.issn.1004-549x.2025.05.017
我国2018-2023年红细胞输血反应分析
Analysis of red blood cell transfusion reactions in China from 2018 to 2023
摘要
Abstract
Objective To analyze the demographic characteristics of patients with red blood cell transfusion reactions,the usage of red blood cell preparations,and the differences in the composition ratio of adverse reactions based on multi-cen-ter data from the Haemovigilance Network,in order to reveal the clinical characteristics of red blood cell transfusion and its underlying issues.Methods Clinical data of patients who experienced transfusion reactions after red blood cell transfusion in the Haemovigilance Network from 2018 to 2023 were collected.The demographic characteristics of patients who experi-enced transfusion reactions with different types of red blood cell preparations,the utilization of these preparations,and the differences of the composition ratios of transfusion reactions were analyzed.Count data were expressed as numbers(n)or percentages(%),and comparisons between groups were performed using the Chi-square test.Results Red blood cell transfusion reactions were more common in females(53.56%),with the majority of patients aged 50-69 years(35.54%).The Han polulation accounted for the vast majority of patients(92.77%),and patients in the hematology and obstetrics/gy-necology departments had a relatively high proportion of transfusion reactions(13.26%and 14.26%,respectively).Leuko-cyte-reduced red blood cells and suspended red blood cells were the most common types of transfusion reactions reported a-mong red blood cell preparations.Allergic reactions and non-hemolytic febrile reactions were the most common transfusion reactions,and there were significant differences in the composition ratios of allergic reactions(χ2=869.89,P<0.05)and non-hemolytic febrile reactions(χ2=812.75,P<0.05)across various types of red blood cell preparations.Conclusion There are differences in the demographic characteristics and composition ratio of transfusion reactions among different red blood cell preparations.The management of red blood cell transfusion reactions should be tailored to patient characteristics and conditions,and the selection and use of blood products should be optimized to reduce or avoid the occurrence of transfu-sion reactions,such as considering the use of washed red blood cells for patients with a history of transfusion allergies or those prone to allergies.关键词
红细胞输注/输血反应/血液预警/患者特征Key words
red blood cell transfusion/transfusion reaction/haemovigilance/patient characteristics分类
医药卫生引用本文复制引用
潘波,刘忠,官笑羽,王珏,潘云龙,何流,徐海霞,纪欣,田力,李玲..我国2018-2023年红细胞输血反应分析[J].中国输血杂志,2025,38(5):704-710,7.基金项目
中国医学科学院中央级公益性科研院所基本科研业务费专项资金(2018PT32016) （2018PT32016）
中国医学科学院医学与健康科技创新工程(2021-I2M-1-060) （2021-I2M-1-060）
