中国输血杂志2025，Vol.38Issue(5)：711-716,6.DOI:10.13303/j.cjbt.issn.1004-549x.2025.05.018
西安市献血者人细小病毒B19既往感染现况调查
Investigation on past human parvovirus B19 infection among blood donors in Xi'an,China
摘要
Abstract
Objective To investigate the distribution characteristics of previous infection of human parvovirus B19(HPV B19)among blood donors in Xi'an,and to provide data support and theoretical basis for formulating individualized and precise blood screening strategies.Methods A total of 970 qualified blood samples tested at Shaanxi Blood Center from August to September 2024 were randomly selected.The levels of HPV B19 IgG antibodies in the serum were detected by enzyme-linked immunosorbent assay(ELISA).The distribution characteristics of the samples were analyzed from the perspectives of age,gender,education level,occupation,blood type and region.Results The positive rate of HPV B19 IgG antibodies among blood donors in Xi'an was 25.26%(245/970),which increased gradually with age(P<0.05).There was no significant difference in the positive rate of HPV B19 IgG antibodies among blood donors of different genders,education levels,occupations,or blood types(P>0.05).Univariate logistic regression analysis showed that past HPV B19 infection was only related to age(P<0.05).The distribution of positive blood samples in 13 districts and counties of Xi'an was counted based on the blood collection sites.The results showed that there was no significant global spatial autocorrela-tion in the distribution of positive samples.Among them,the Weiyang District and Beilin District exhibited a"high-high"cluster(P<0.05),while Chang'an District exhibited a"low-high"cluster(P<0.01).Conclusion A certain proportion of blood donors in Xi'an showed past infection with HPV B19,which was only correlated with age and demonstrated an up-ward trend.It is recommended to continue expanding the screening scope and incorporate screening for this virus in blood transfusion processes involving susceptible populations.关键词
人细小病毒B19/献血者/免疫球蛋白G/流行病学研究Key words
human parvovirus B19(HPV B19)/blood donors/immunoglobulin G/epidemiological study分类
医药卫生引用本文复制引用
赵柏雅,褚晓月,金钰淇,马超锋..西安市献血者人细小病毒B19既往感染现况调查[J].中国输血杂志,2025,38(5):711-716,6.基金项目
西安英才计划-菁英(创新人才)项目(XAYC220046) （创新人才）
陕西省重点研发计划项目资助(2024SF-YBXM-272) （2024SF-YBXM-272）
2022年陕西省卫生健康科研项目(2022D050) （2022D050）
陕西省科技厅重点研发计划(2025CY-YBXM-138) （2025CY-YBXM-138）
西安市科技局科研项目(23YXYJ0013) （23YXYJ0013）
中国输血协会威高基金(CS-BT-WG-2024-04) （CS-BT-WG-2024-04）
