中国兽医杂志2025，Vol.61Issue(5)：97-103,7.DOI:10.20157/j.cnki.zgsyzz.2025.05.012
赤羽病病毒非结构蛋白的作用及其机制
Role and Mechanism of Non-Structural Proteins of Akabane Virus
摘要
Abstract
Akabane virus(AKAV)primarily causes a viral infectious disease in cattle and sheep,characterized by abortion,premature birth,stillbirth,and congenital deformities,such as arthrogryposis-hydranencephaly syndrome(A-H syndrome).The non-structural proteins NSs and NSm play a crucial role in the virus's replication,pathogenicity,and immune evasion.This paper reviews the functions and characteristics of the non-structural proteins NSs and NSm in AKAV,their impact on AKAV replication and evolution,and the host cell immune responses triggered by these proteins.The aim is to provide insights into the pathogenic mechanisms of AKAV non-structural proteins and offer a reference for the design of effective vaccines and immunological prevention and treatment strategies.关键词
赤羽病病毒/非结构蛋白/功能/免疫逃逸/病毒复制Key words
akabane virus/non-structural protein/function/immune escape/virus replication分类
农业科技引用本文复制引用
黄俊杰,张克山,张苗苗,赵登率,李平,张远航,赵孟孟,覃丽梅,陈胜锋,高寒..赤羽病病毒非结构蛋白的作用及其机制[J].中国兽医杂志,2025,61(5):97-103,7.基金项目
以农业领域为单元的广东省现代农业产业共性关键技术研发创新团队建设项目[生物安全与防控(动物方向)共性关键技术](2024CXTD15) （动物方向）
国家重点研发计划子课题(2023YFD1801301,2023YFD1801302) （2023YFD1801301,2023YFD1801302）
佛山高层次人才启动项目(BKS111000,CGZ07001) （BKS111000,CGZ07001）
