摘要
Abstract
Objective To analyze the clinical features and influencing factors of basal ganglia aphasia after stroke.Methods 120 patients with basal ganglia stroke admitted to the Department of Intensive Care Medicine of the First People's Hospital of Suqian City from August 2022 to May 2024 were selected as the study objects.According to whether aphasia occurred after stroke,they were divided into an aphasia group(32 cases)and a normal speech group(88 cases).The baseline data,such as clinical general data and laboratory examination indicators,were collected,and clinical language scale and neuropsychological scale were evaluated in the both groups.The clinical features of basal ganglia aphasia after stroke were analyzed,and the influencing factors of basal ganglia aphasia after stroke were analyzed by multivariate Logistic regression.Results There were significant differences in age and lesion site between the aphasia group and the normal speech group(P<0.05).On the aphasia battery of Chinese(ABC),Fluency,Reading,Nomenclature,Listening Comprehension,aphasia quotient,AQ score,Montreal cognitive assessment Scale(MoCA)score and Mini-Mental State examination(MMSE)score were all lower than those of the normal speech group(P<0.05).Patient health questionnaire(PHQ-9)score and Hamilton depression scale-17 score of aphasia group HAMD-17 score and Hamilton anxiety scale-17 score were higher than those of the normal speech group(P<0.05).Multivariate Logistic regression analysis showed that age increased(OR=8.776,95%CI=2.479-31.069),lesion location was left basal ganglia(OR=6.430,95%CI=2.019-20.478),MoCA score decreased(OR=3.838,MOCA score decreased(OR=3.838.95%CI=1.513～9.738),MMSE score decreased(OR=2.672,95%CI=1.183～6.040),PHQ-9 score increased(OR=2.399,95%CI=1.187～4.848),HAMD-17 score increased(OR=3.575,95%CI=1.293-9.887)and increased HAMA-17 score(OR=3.261,95%CI=1.077-9.869)were the influential factors for basal ganglia aphasia after stroke(P<0.05).Conclusion The patients with basal ganglia aphasia after stroke have impaired language function,and may show cognitive dysfunction and obvious anxiety and depression.The occurrence of aphasia is related to age,left basal ganglia lesion,reduced cognitive function,and increased anxiety and depression.关键词
脑卒中/基底节/失语症/临床特征/影响因素Key words
Stroke/Basal ganglia/Aphasia/Clinical features/Influencing factor分类
社会科学
