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首页|期刊导航|中国医科大学学报|TG/HDL-C、MPV/PC比值对老年冠状动脉粥样硬化性心脏病患者PCI术后支架内再狭窄的预测价值

TG/HDL-C、MPV/PC比值对老年冠状动脉粥样硬化性心脏病患者PCI术后支架内再狭窄的预测价值

郭晓冬 张海云 孙秋愿 方居正

中国医科大学学报2025,Vol.54Issue(5):442-447,6.
中国医科大学学报2025,Vol.54Issue(5):442-447,6.DOI:10.12007/j.issn.0258-4646.2025.05.011

TG/HDL-C、MPV/PC比值对老年冠状动脉粥样硬化性心脏病患者PCI术后支架内再狭窄的预测价值

Predictive value of the TG/HDL-C and MPV/PC ratios for in-stent restenosis after PCI in elderly patients with coronary heart disease

郭晓冬 1张海云 1孙秋愿 1方居正2

作者信息

  • 1. 平煤神马医疗集团总医院心血管内科,河南 平顶山 467099
  • 2. 平顶山中医医院心血管内科,河南 平顶山 467099
  • 折叠

摘要

Abstract

Objective To explore the predictive value of the triglycerides/high-density lipoprotein cholesterol(TG/HDL-C)ratio com-bined with the mean platelet volume/platelet count(MPV/PC)ratio for in-stent restenosis(ISR)after percutaneous coronary intervention(PCI)in elderly patients with coronary heart disease.Methods A total of 240 elderly patients with coronary heart disease admitted at the Pingmei Shenma Medical Group General Hospital from January 2021 to January 2023 were selected and divided into the ISR(36 cases)and non-ISR(204 cases)groups based on whether ISR occurred 6 months after PCI.The clinical data,TG/HDL-C ratio,and MPV/PC ratio of the two groups were compared,and Pearson's correlation analysis was used to analyze the correlation between the TG/HDL-C and MPV/PC ratios.Multivariate logistic regression analysis was used to analyze the relationship between the TG/HDL-C ratio,MPV/PC ratio,and ISR after PCI.The receiver operating characteristic(ROC)curve and area under the curve(AUC)were used to evaluate the predictive value of the TG/HDL-C and MPV/PC ratios for ISR after PCI in older patients with coronary heart disease.Results There were statisti-cally significant differences in the comparisons of diabetes,hypertension,the degree of coronary artery stenosis,and stent diameter between the two groups(P<0.05);the ISR group had higher TG levels,MPV levels,TG/HDL-C ratios,and MPV/PC ratios,and lower HDL-C and PC levels compared to the non-ISR group(P<0.05);the TG/HDL-C ratio was positively correlated with the MPV/PC ratio(P<0.05);the TG/HDL-C and MPV/PC ratios were independently associated with ISR after PCI in older patients with coronary heart disease(P<0.05);and the AUC for predicting ISR after PCI in older patients with coronary heart disease was 0.759 and 0.784 for the TG/HDL-C and MPV/PC ratios,respectively,and the combined prediction showed an AUC of 0.921,which was superior to that of either alone.Conclusion The TG/HDL-C and MPV/PC ratios were significantly correlated with ISR in elderly patients with coronary heart disease after PCI,and their combined predictive value was reliable.

关键词

冠状动脉粥样硬化性心脏病/经皮冠状动脉介入治疗/支架内再狭窄/甘油三酯/高密度脂蛋白胆固醇比值/血小板平均体积/血小板计数比值/预测价值

Key words

coronary heart disease/percutaneous coronary intervention/in-stent restenosis/triglyceride/high-density lipoprotein cho-lesterol ratio/mean platelet volume/platelet count ratio/predictive value

分类

医药卫生

引用本文复制引用

郭晓冬,张海云,孙秋愿,方居正..TG/HDL-C、MPV/PC比值对老年冠状动脉粥样硬化性心脏病患者PCI术后支架内再狭窄的预测价值[J].中国医科大学学报,2025,54(5):442-447,6.

基金项目

河南省中医药科学研究专项课题(20-21ZY2288) (20-21ZY2288)

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