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代谢组学在焦虑障碍中的应用

张晰越 邵小骏 林永忠 朱刚

中国医科大学学报2025,Vol.54Issue(5):461-465,5.
中国医科大学学报2025,Vol.54Issue(5):461-465,5.DOI:10.12007/j.issn.0258-4646.2025.05.014

代谢组学在焦虑障碍中的应用

Application of metabolomics in anxiety disorders

张晰越 1邵小骏 2林永忠 3朱刚2

作者信息

  • 1. 中国医科大学附属第一医院精神科,沈阳 110001||大连医科大学附属第二医院神经内科,辽宁 大连 116027
  • 2. 中国医科大学附属第一医院精神科,沈阳 110001
  • 3. 大连医科大学附属第二医院神经内科,辽宁 大连 116027
  • 折叠

摘要

Abstract

Anxiety disorders are psychiatric conditions characterized by high prevalence,chronicity,and comorbidity.The World Health Organization has listed anxiety disorders as a cause of health-related disabilities.Metabolomics can be used to qualitatively and quantita-tively analyze metabolites in organisms using modern analytical techniques,comprehensively revealing the overall characteristics of meta-bolic changes in the body and providing novel insights into diseases.It is important to identify potential biomarkers associated with anxiety disorders by investigating perturbations in metabolites and metabolic pathways in patients with anxiety disorders.This review addresses the application of metabolomics in anxiety disorders to provide a basis for revealing their pathogenesis,early diagnosis,and efficacy evalu-ation.

关键词

焦虑障碍/代谢组学/生物标志物

Key words

anxiety disorder/metabolomics/biomarker

分类

医药卫生

引用本文复制引用

张晰越,邵小骏,林永忠,朱刚..代谢组学在焦虑障碍中的应用[J].中国医科大学学报,2025,54(5):461-465,5.

基金项目

国家自然科学基金(81571237) (81571237)

辽宁省经济社会发展合作课题(2024lslybhzkt-18) (2024lslybhzkt-18)

中国医科大学学报

OA北大核心

0258-4646

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