摘要
Abstract
Objective:To investigate the effect of low temperature plasma adenotonsillectomy in children with obstructive sleep apnea syndrome.Method:A total of 799 children with obstructive sleep apnea syndrome who needed surgical treatment in Zhuhai Center for Maternal and Child Health Care from May 2022 to May 2023 were selected as the study objects.Children were randomly divided into control group(n=399)and observation group(n=400).The control group was treated with conventional adenotonsillectomy,and the observation group was treated with low temperature plasma adenotonsillectomy.The perioperative indexes(intraoperative blood loss,operation time,postoperative pain duration,tunica albuginea shedding time,postoperative hospital stay),ventilation function[oxygen desaturation index,minimum oxygen saturation,longest apnea duration,respiratory disturbance index],serum chemokine levels[chemokine ligand 2(CCL2),chemokine ligand 21(CCL21)]and immune function indexes[immunoglobulin G(IgG),immunoglobulin A(IgA),immunoglobulin M(IgM)]were compared between the two groups,and the postoperative bleeding conditions were recorded between the two groups.Result:The unica albuginea shedding time in the observation group was longer than that in the control group,the intraoperative blood loss was less than that in the control group,and the operation time,postoperative pain duration and postoperative hospital stay were shorter than those in the control group(P<0.05).4 weeks after surgery,the minimum oxygen saturation were increased in both groups,the longest apnea duration were shortened,and the oxygen desaturation index and respiratory disturbance index were decreased(P<0.05).4 weeks after surgery,the minimum oxygen saturation of the observation group was higher than that of the control group,the longest apnea time was shorter than that of the control group,and the oxygen desaturation index and respiratory disturbance were less than those of the control group(P<0.05).4 weeks after surgery,CCL21 were decreased in both groups,that in observation group was lower than that in control group,CCL2 were increased,that in observation group was higher than that in control group(P<0.05).4 weeks after surgery,the levels of IgG,IgA and IgM were decreased in both groups,but those in the observation group were higher than those in the control group(P<0.05).The incidence of primary hemorrhage in observation group was higher than that in control group,and the incidence of delayed bleeding was lower than that in control group(P<0.05).There was no significant difference in the incidence of total bleeding between the two groups(P>0.05).Conclusion:Low temperature plasma adenotonsillectomy is beneficial to the postoperative recovery and improvement of ventilation function in children with obstructive sleep apnea syndrome,and can improve the levels of serum chemokines and immune function,and reduce the occurrence of delayed bleeding.关键词
阻塞性睡眠呼吸暂停综合征/低温等离子腺样体扁桃体切除术/免疫功能/迟发性出血Key words
Obstructive sleep apnea syndrome/Low temperature plasma adenotonsillectomy/Immune function/Delayed bleeding
