中国医学创新2025，Vol.22Issue(14)：11-14,4.DOI:10.3969/j.issn.1674-4985.2025.14.003
左卡尼汀联合人促红素对血液透析贫血患者血红蛋白、铁生物标志物的影响
Effects of Levocarnitine Combined with Human Erythropoietin on Hemoglobin and Iron Biomarkers in Anemia Patients Undergoing Hemodialysis
宋瑞龙 1叶益舟 1黄艳莉1
作者信息
- 1. 龙南市第一人民医院肾内科 江西 龙南 341700
- 折叠
摘要
Abstract
Objective:To explore the effects of Levocarnitine combined with Human Erythropoietin on hemoglobin(Hb)and iron biomarkers in anemia patients underwent hemodialysis.Method:A total of 102 anemia patients underwent hemodialysis admitted to Longnan First People's Hospital from June 2022 to June 2024 were selected as the study objects,and were divided into Human Erythropoietin group(n=51)and combined group(n=51)according to envelope drawing method.Human Erythropoietin group was treated with Human Erythropoietin,and the combined group was treated with Levocarnitine combined with Human Erythropoietin.The clinical efficacy,iron biomarkers,anemia indexes and adverse reactions were compared between the two groups.Result:The total clinical effective rate of combined group was higher than that of Human Erythropoietin group,the difference was statistically significant(P<0.05).After treatment,serum ferritin(SF),transferrin saturation(TSAT)and transferrin(TRF)in combined group were higher than those in Human Erythropoietin group,the differences were statistically significant(P<0.05).After treatment,Hb,red blood cell count(RBC)and hematocrit(HCT)in combined group were higher than those in Human Erythropoietin group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Levocarnitine combined with Human Erythropoietin in the treatment of anemia patients undergoing hemodialysis can significantly improve the levels of hemoglobin and iron biomarkers,with obvious curative effect and high safety.关键词
左卡尼汀/人促红素/血液透析/贫血/血红蛋白/铁生物标志物Key words
Levocarnitine/Human Erythropoietin/Hemodialysis/Anemia/Hemoglobin/Iron biomarkers引用本文复制引用
宋瑞龙,叶益舟,黄艳莉..左卡尼汀联合人促红素对血液透析贫血患者血红蛋白、铁生物标志物的影响[J].中国医学创新,2025,22(14):11-14,4.
