中国医学创新2025，Vol.22Issue(14)：92-96,5.DOI:10.3969/j.issn.1674-4985.2025.14.020
盐酸纳布啡在全麻下扁桃体摘除术及腺样体切除术患儿中的应用效果
Application Effect of Nalbuphine Hydrochloride in Enucleation of Tonsil and Adenoidectomy under General Anesthesia
摘要
Abstract
Objective:To study the application effect of Nalbuphine Hydrochloride in enucleation of tonsil and adenoidectomy under general anesthesia,and its influence on hemodynamics and pain in children during recovery period.Method:A total of 80 children with tonsil or adenoid lesions who needed surgical treatment in Gao'an People's Hospital from April to October 2024 were selected,and were divided into control group and experimental group by random number table method,with 40 cases in each group.In the control group,Penehyclidine Hydrochloride,Fentanyl Citrate,Propofol and Rocuronium were used for anesthesia induction,and Sevoflurane,Remifentanil and Rocuronium were used for anesthesia maintenance.The experimental group replaced Fentanyl Citrate with Nalbuphine Hydrochloride,and the rest was consistent with the control group.The incidence of postoperative agitation,delayed recovery,agitation and pain scores,and heart rate and mean arterial pressure before surgery,at tracheal extubation and 10 min after extubation were compared between the two groups,and the incidence of adverse reactions was statistically counted.Result:The incidence of postoperative agitation,the scores of pediatric anesthesia emergence delirium scale(PAED)and face,legs,activity,cry,consolability scale(FLACC)in the experimental group were lower than those in the control group(P<0.05).There was no significant difference in the incidence of delayed recovery between the two groups(P>0.05).There were no significant differences in heart rate and mean arterial pressure before surgery between the two groups(P>0.05);the heart rate and mean arterial pressure of the control group at trachea extubation and 10 min after extubation were higher than those before surgery,and the heart rate of the experimental group 10 min after extubation was lower than that before surgery(P<0.05);the heart rate and mean arterial pressure of the experimental group at trachea extubation and 10 min after extubation were significantly lower than those of the control group(P<0.05).The total incidence of adverse reactions in the experimental group was significantly lower than that in the control group(P<0.05).Conclusion:Nalbuphine Hydrochloride has a good application effect in enucleation of tonsil and adenoidectomy under general anesthesia,which can significantly reduce postoperative pain and stabilize hemodynamics,and reduce the occurrence of adverse reactions.关键词
盐酸纳布啡/芬太尼/扁桃体摘除术/腺样体切除术/血流动力学/疼痛Key words
Nalbuphine Hydrochloride/Fentanyl/Enucleation of tonsil/Adenoidectomy/Hemodynamics/Pain引用本文复制引用
毛银泉,高静,罗子莹..盐酸纳布啡在全麻下扁桃体摘除术及腺样体切除术患儿中的应用效果[J].中国医学创新,2025,22(14):92-96,5.基金项目
宜春市指导性科技计划项目(JXYC2024KSA319) （JXYC2024KSA319）
