中国医学创新2025,Vol.22Issue(14):178-184,7.DOI:10.3969/j.issn.1674-4985.2025.14.039
肺结核后肺癌的发病机制研究进展
Research Progress in Pathogenesis of Post-tuberculosis Lung Cancer
摘要
Abstract
Both lung cancer and tuberculosis are major public health problems worldwide,taking millions of lives each year.Pulmonary tuberculosis is characterized by a high incidence rate,high drug resistance rate,and high disability rate.Lung cancer is the leading cause of morbidity and mortality in malignant tumors worldwide,posing a threat to global health.In recent years,many studies indicated that pre-existing pulmonary tuberculosis is an independent risk factor for lung cancer.Tuberculosis-related chronic inflammation,abnormal epidermal growth factor signaling pathway,immune escape,the expression of tuberculosis bacteria-related protein,scar repair,and other factors may contribute to the pathogenesis of post-tuberculosis lung cancer.This review addresses the pathogenesis of post-tuberculosis lung cancer.关键词
肺癌/肺结核/发病机制/结核分枝杆菌Key words
Lung cancer/Pulmonary tuberculosis/Mechanism/Mycobacterium tuberculosis引用本文复制引用
岑晓红,梁业金,钟金媚,何鸿杰,蒋玉洁..肺结核后肺癌的发病机制研究进展[J].中国医学创新,2025,22(14):178-184,7.基金项目
国家自然科学基金项目(81860021) (81860021)
广西自然科学基金面上项目(2021GXNSFAA325003) (2021GXNSFAA325003)