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肺结核后肺癌的发病机制研究进展

岑晓红 梁业金 钟金媚 何鸿杰 蒋玉洁

中国医学创新2025,Vol.22Issue(14):178-184,7.
中国医学创新2025,Vol.22Issue(14):178-184,7.DOI:10.3969/j.issn.1674-4985.2025.14.039

肺结核后肺癌的发病机制研究进展

Research Progress in Pathogenesis of Post-tuberculosis Lung Cancer

岑晓红 1梁业金 1钟金媚 1何鸿杰 1蒋玉洁2

作者信息

  • 1. 右江民族医学院研究生院 广西 百色 533000
  • 2. 右江民族医学院附属医院呼吸与危重症医学科 广西 百色 533000
  • 折叠

摘要

Abstract

Both lung cancer and tuberculosis are major public health problems worldwide,taking millions of lives each year.Pulmonary tuberculosis is characterized by a high incidence rate,high drug resistance rate,and high disability rate.Lung cancer is the leading cause of morbidity and mortality in malignant tumors worldwide,posing a threat to global health.In recent years,many studies indicated that pre-existing pulmonary tuberculosis is an independent risk factor for lung cancer.Tuberculosis-related chronic inflammation,abnormal epidermal growth factor signaling pathway,immune escape,the expression of tuberculosis bacteria-related protein,scar repair,and other factors may contribute to the pathogenesis of post-tuberculosis lung cancer.This review addresses the pathogenesis of post-tuberculosis lung cancer.

关键词

肺癌/肺结核/发病机制/结核分枝杆菌

Key words

Lung cancer/Pulmonary tuberculosis/Mechanism/Mycobacterium tuberculosis

引用本文复制引用

岑晓红,梁业金,钟金媚,何鸿杰,蒋玉洁..肺结核后肺癌的发病机制研究进展[J].中国医学创新,2025,22(14):178-184,7.

基金项目

国家自然科学基金项目(81860021) (81860021)

广西自然科学基金面上项目(2021GXNSFAA325003) (2021GXNSFAA325003)

中国医学创新

1674-4985

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