中国医学前沿杂志（电子版）2025，Vol.17Issue(4)：99-103,5.DOI:10.12037/YXQY.2025.04-15
孙氏手术治疗主动脉夹层术后发生严重低氧血症的危险因素分析
Analysis of risk factors for severe hypoxaemia in patients with aortic dissection after Sun's procedure
摘要
Abstract
Objective To analyze the risk factors for severe hypoxaemia in patients with aortic dissection(AD)after Sun's procedure.Methods A total of 214 patients with AD who underwent Sun's procedure between January 2020 to June 2022 at the Department of Cardiac Surgery of Tianjin Chest Hospital were enrolled.The clinical data were retrospectively collected.According to the 2012 Berlin criteria for acute respiratory distress syndrome,combined with arterial blood gas analysis results,they were divided into severe hypoxaemia group and non-severe hypoxaemia group.Univariate and multivariate logistic regression analysis were used to screen the risk factors for severe hypoxaemia after Sun's procedure,and a prediction model was established based on these risk factors.The area under the receiver operating characteristic(ROC)curve was used to determine the predictive value of the model for the occurrence of severe hypoxaemia in patients with AD after Sun's procedure.Results Among the 214 patients,68 patients developed severe hypoxemia occurred,with an incidence rate of 31.8%.Comparing the clinical data of the two groups of patients,the results revealed that there were statistically significant differences in body mass index(BMI),D-dimer level,and preoperative serum creatinine values(P<0.05).Multivariate logistic regression analysis revealed that BMI,D-dimer level,and preoperative serum creatinine value were independent risk factors associated with severe hypoxaemia after Sun's procedure(P<0.05).By leveraging the results of multivariate analysis,a predictive model was established,a receiver operating characteristic curve was drawn,showing that the model had a predictive accuracy of 72.3%(95%confidence interval:0.65-0.79)for severe hypoxaemia.Conclusions BMI,D-dimer level,and preoperative serum creatinine value are risk factors for severe hypoxaemia after Sun's procedure.Patients who are overweight,have high preoperative creatinine values,and have D-dimer levels greater than 20 μg/ml are prone to severe hypoxaemia after Sun's procedure.关键词
孙氏手术/严重低氧血症/主动脉夹层/危险因素Key words
Sun's procedure/Severe hypoxaemia/Aortic dissection/Risk factors引用本文复制引用
白耀邦,吴振华,齐玉娟,白云鹏,陈庆良..孙氏手术治疗主动脉夹层术后发生严重低氧血症的危险因素分析[J].中国医学前沿杂志（电子版）,2025,17(4):99-103,5.基金项目
天津市医学重点学科(专科)建设项目(TJYXZDXK-042A) Tianjin Key Medical Discipline(Specialty)Construction Project(TJYXZDXK-042A) （专科）
