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肝癌早诊早治项目筛查与随访结果:基于广西扶绥县2011-2020年数据分析

吕瑞博 安三春 李云西 张朝钧 丘洁 陈晓梅 罗云波 邓伟 黄天壬

中国癌症防治杂志2025,Vol.17Issue(2):139-144,6.
中国癌症防治杂志2025,Vol.17Issue(2):139-144,6.DOI:10.3969/j.issn.1674-5671.2025.02.02

肝癌早诊早治项目筛查与随访结果:基于广西扶绥县2011-2020年数据分析

Screening and follow-up results of the early diagnosis and treatment program for liver can-cer:a data analysis based on Fusui County,Guangxi,2011-2020

吕瑞博 1安三春 1李云西 2张朝钧 1丘洁 1陈晓梅 1罗云波 1邓伟 1黄天壬1

作者信息

  • 1. 530021 南宁 广西医科大学附属肿瘤医院实验研究部
  • 2. 532200 崇左 扶绥县人民医院预防保健科
  • 折叠

摘要

Abstract

Objective To analyze the screening and follow-up outcomes of liver cancer early diagnosis and treatment program in Fusui County,Guangxi,from 2011 to 2020.Methods A stratified cluster sampling method was employed to enroll the residents aged 35-64 years old for male and 45-64 years old for female,and other residents who were not within this age range but had cases of liver cancer in their immediate family members in Fusui County from 2011 to 2020 as the study subjects.High-risk populations of liver cancer were identified through questionnaires and hepatitis B surface antigen(HBsAg)testing.These individuals underwent combined screening via liver ultrasound and alpha fetoprotein(AFP)testing.The compliance of participating in the early diagnosis and treatment of liver cancer program was analyzed,as well as the detection rate,early diagnosis rate,treatment rate and prognosis of liver cancer.Results From 2011 to 2020,a total of 27,613 high-risk groups were assessed in Fusui County,Guangxi,of which a total of 14,012 people com-pleted combined screening for liver cancer,with a screening participation rate of 50.74%;120 liver cancer cases were found and di-agnosed,with a detection rate of 0.86%.The detection rate of liver cancer in males was significantly higher than that in females(1.12%vs 0.51%,P<0.001).The detection rates of liver cancer in the age groups of 35-44 years old,45-54 years old,and ≥55 years old were 0.67%,0.92%,and 1.05%,respectively,and the difference was not statistically significant(P=0.169).Among the 120 cases of liver cancer,the early diagnosis and treatment rates were 60.83%(73/120)and 91.67%(110/120)respectively.Overall 1-,3-,and 5-year survival rates were 66.67%,33.33%,and 20.83%,respectively,while early-state liver cancer survival rates were 75.34%,36.99%,and 24.66%,respectively.Conclusions The early diagnosis and treatment program in Fusui County can effectively identifies liver cancer cases,enables timely intervention,and prolongs survival through early diagnosis.

关键词

肝癌/早诊早治/筛查/广西

Key words

Liver cancer/Early diagnosis and treatment/Screening/Guangxi

分类

临床医学

引用本文复制引用

吕瑞博,安三春,李云西,张朝钧,丘洁,陈晓梅,罗云波,邓伟,黄天壬..肝癌早诊早治项目筛查与随访结果:基于广西扶绥县2011-2020年数据分析[J].中国癌症防治杂志,2025,17(2):139-144,6.

基金项目

国家自然科学基金项目(82160638) (82160638)

中国癌症防治杂志

1674-5671

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