中国癌症防治杂志2025，Vol.17Issue(2)：145-149,5.DOI:10.3969/j.issn.1674-5671.2025.02.03
肝癌住院患者生存特征分析:基于广西某肿瘤医院的十年队列随访(2010-2020年)
Analysis of survival characteristics in liver cancer inpatients:a 10-year follow-up cohort from a cancer hospital in Guangxi(2010-2020)
摘要
Abstract
Objective To analyze survival status of liver cancer inpatients in a cancer hospital in Guangxi from 2010 to 2020.Methods Based on the hospital registration system,an active-passive follow-up was performed for liver cancer inpatients in a cancer hospital in Guangxi from January 2010 to December 2020,with follow-up ending on August 6,2024.Kaplan-Meier survival analysis was used to calculate survival rates.Wilcoxon rank-sum was used to analyze survival differences by age,sex,Barcelona Clinical Liver Cancer(BCLC),and treatment periods.Results A total of 12,177 liver cancer patients were included,with an average age of(60.03±11.79)years,and a higher proportion of males than females(86.19％vs 13.81％).The median overall survival was 14.53 months,with 1-,3-,5-,and 10-year survival rates of 52.25％,34.20％,28.11％,and 19.89％,respectively,the survival rate of male patients was lower than that of female patients at all timepoints(P＜0.001).The survival curves differed statistically significant among age groups,with lower 5-year survival rates in the＜40(26.55％)and ≥80(19.21％)age groups compared with the 40-79 age group(27.97％-28.48％).The 5-year survival rates of patients in BCLC stages A,B,C,and D were 69.56％,42.95％,15.72％,and 6.20％,respectively(P＜0.001).The 1-,3-,and 5-year survival rates for patients from 2010 to 2015 were 50.49％,32.49％,and 26.41％,respectively,which improved to 53.72％,35.60％,and 29.45％during 2016-2020,with statistically significant differences(P＜0.001).Conclusions The long-term survival rates of liver cancer inpatients in Guangxi from 2016 to 2020 showed a significant upward trend,but remained at a relatively low level.Patients with young/old age,male,and advanced BCLC stages still face challenges in survival rates,and should be prioritized focus.Comprehensive prevention and control measures for liver cancer should be further strengthened.关键词
肝癌/肿瘤登记/医院登记/随访/生存率Key words
Liver Cancer/Cancer registry/Hospital registry/Follow-up/Survival rate分类
临床医学引用本文复制引用
梁秀妹,陈惟义,周子寒,马良,吴芸,卢香宁,向邦德,余红平,吕汉斌..肝癌住院患者生存特征分析:基于广西某肿瘤医院的十年队列随访(2010-2020年)[J].中国癌症防治杂志,2025,17(2):145-149,5.基金项目
广西自然科学基金重点项目区域高发疾病研究联合专项资助(2024GXNSFDA010040) （2024GXNSFDA010040）
广西医疗卫生适宜技术开发与推广应用项目(S2022112) （S2022112）
广西壮族自治区卫生健康委员会自筹经费科研课题(Z-A20240717) （Z-A20240717）
