中国癌症防治杂志2025,Vol.17Issue(2):250-256,7.DOI:10.3969/j.issn.1674-5671.2025.02.18
立体定向放射治疗在寡转移和寡进展肾细胞癌中应用的研究进展
Research advances in the application of stereotactic body radiation therapy for oligometastatic and oligoprogressive renal cell carcinoma
朱俊铭 1邓红彬 1曹欣怡1
作者信息
- 1. 400016 重庆 重庆医科大学附属第一医院肿瘤科
- 折叠
摘要
Abstract
Renal cell carcinoma(RCC)is one of the most common malignant tumors of the urinary system,with metastatic dissemina-tion occurring at substantial frequencies.This malignancy demonstrates limited sensitivity to chemotherapy drugs and conventional radiotherapy,and the current treatment for advanced-stage RCC primarily relies on targeted therapy and immunotherapy.Emerging evidence indicates that RCC does not show strong resistance to hypofractionated radiotherapy,as evidenced by significantly diminished tumor cell viability when single-fraction doses escalate to 6 Gy.In recent years,stereotactic body radiation therapy has been widely used in the local disease control for advanced RCC,capitalizing on to its characteristics of ablative fractional dose,high precision,and non-invasiveness,demonstrates an excellent local tumor control rate of the lesion with acceptable reaction.This article reviews the progress in the application of stereotactic body radiation therapy in oligometastatic and oligoprogressive RCC.关键词
立体定向放射治疗/RCC/寡转移/寡进展/靶向治疗/免疫治疗Key words
Stereotactic body radiation therapy/Renal cell carcinoma/Oligometastatic/Oligoprogressive/Targeted therapy/Immu-notherapy分类
医药卫生引用本文复制引用
朱俊铭,邓红彬,曹欣怡..立体定向放射治疗在寡转移和寡进展肾细胞癌中应用的研究进展[J].中国癌症防治杂志,2025,17(2):250-256,7.