中国医药科学2025，Vol.15Issue(8)：22-25,4.DOI:10.20116/j.issn2095-0616.2025.08.04
SIRT6在呼吸系统疾病中的研究进展
Research progress of SIRT6 in respiratory system diseases
摘要
Abstract
As a nicotinamide adenine dinucleotide dependent histone,recombinant sirtuin 6(SIRT6)is an important member of the sirtuins family and belongs to Class Ⅲ histone deacetylase(HDAC).Its NAD+dependent histone deacetylase,adenosine diphosphate ribosyltransferase,and deacetylase activities have been discovered,and it plays a key role in regulating various life processes in the body,especially in cancer,inflammation,oxidative stress,deoxyribonucleic acid damage and repair,telomere maintenance,genome stability,and other physiological regulation.This article review the research progress of SIRT6 in some respiratory system diseases.关键词
SIRT6/NAD+/组蛋白去乙酰化酶/呼吸系统疾病/研究进展Key words
Silent mating-type information regulation-related protein type 6/NAD+/Histone deacetylase/Respiratory system diseases/Research progress分类
临床医学引用本文复制引用
齐艳,孙云晖..SIRT6在呼吸系统疾病中的研究进展[J].中国医药科学,2025,15(8):22-25,4.基金项目
黑龙江省卫生健康委员会科研课题(2020-323). （2020-323）
