中华临床免疫和变态反应杂志2025，Vol.19Issue(2)：127-133,7.DOI:10.3969/j.issn.1673-8705.2025.02.008
调节性T细胞在类风湿关节炎中的研究进展
Research advances of regulatory T cells in rheumatoid arthritis
李焕成 1苏勤怡 1刘子策 2王彩虹 1李小峰 1张升校1
作者信息
- 1. 030001 太原,山西医科大学第二医院风湿免疫科
- 2. 100053 北京,首都医科大学宣武医院麻醉手术科
- 折叠
摘要
Abstract
Rheumatoid arthritis(RA)is a chronic,progressive autoimmune disease characterized by dysregulated immune response and genetic factors.Regulatory T cells(Tregs)are a special type of immune cells that play a crucial role in suppressing and regulating the activity of other immune cells to maintain immune system homeostasis and have been implicated in the pathogenesis of RA.Studies have shown that quantitative and functional impairment of Tregs in RA patients,leading to immune dysregulation.Restoring Treg function and quantity holds promise as a therapeutic strategy for RA.This review provides an overview of the latest ad-vances in research on Treg cells in RA,with a focus on therapeutic strategies aimed at restoring Treg function and quantity.The aim is to provide insights and guidance for improving the therapeutic effect of RA and promo-ting further research and clinical application in this field.关键词
类风湿关节炎/调节性T细胞/免疫调节Key words
arthritis,rheumatoid/T lymphocytes,regulatory/immunomodulation引用本文复制引用
李焕成,苏勤怡,刘子策,王彩虹,李小峰,张升校..调节性T细胞在类风湿关节炎中的研究进展[J].中华临床免疫和变态反应杂志,2025,19(2):127-133,7.
