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基因编辑技术在畜禽育种中的应用

汪林丽 韩红兵

中国畜禽种业2025,Vol.21Issue(4):136-154,19.
中国畜禽种业2025,Vol.21Issue(4):136-154,19.

基因编辑技术在畜禽育种中的应用

Applications of Gene Editing Technology in Livestock and Poultry Breeding

汪林丽 1韩红兵1

作者信息

  • 1. 禽畜遗传改良北京市重点实验室/中国农业大学动物科技学院,北京 100193||农业与农村部动物遗传育种与繁育重点实验室,北京 100193
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摘要

Abstract

With the increasing demands for animal health,production efficiency,and product quality in livestock farming,traditional breeding methods face significant challenges,including long cycles,slow progress,and an inability to precisely regulate traits.The rapid development of gene-editing technologies,particularly the application of the CRISPR/Cas system,offers a promising opportu-nity to overcome these bottlenecks.Gene-editing technologies have not only advanced disease-resistant breeding in economically important animals such as pigs,cattle,sheep,and poultry,but have also demonstrated significant efficacy in combating major ani-mal diseases like african swine fever,porcine reproductive and respiratory syndrome,and avian influenza.Furthermore,they enable the precise regulation of genes related to growth,reproduction,and feed conversion efficiency,thereby improving animal performance,meat quality,and fat content.However,technical safety,ethical concerns,and regulatory challenges necessitate further investigation and standardization to promote the sustainable development of gene-editing technologies in animal breeding,providing crucial insights for exploring innovative applications of gene-editing technologies in this field.

关键词

基因编辑/CRISPR/Cas/动物育种/抗病育种/生产性能改良

Key words

Gene editing/CRISPR/Cas/Animal breeding/Disease-resistant breeding/Production performance improvement

分类

农业科技

引用本文复制引用

汪林丽,韩红兵..基因编辑技术在畜禽育种中的应用[J].中国畜禽种业,2025,21(4):136-154,19.

基金项目

科技创新2030-农业生物育种重大项目(2022ZD04013) (2022ZD04013)

中国农业大学基本科研业务费专项资金项目(2022TC025) (2022TC025)

拼多多-中国农业大学研究基金(PC2023A01004). (PC2023A01004)

中国畜禽种业

1673-4556

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