中外医学研究2025，Vol.23Issue(11)：180-184,5.DOI:10.14033/j.cnki.cfmr.2025.11.048
MRI多模态成像在帕金森病合并认知功能障碍患者大脑微观结构与功能的研究进展
Research Progress of MRI Multimodal Imaging in Brain Microstructure and Function of Patients with Parkinson's Disease and Cognitive Impairment
亚库甫·尔肯 1丁爽1
作者信息
- 1. 新疆医科大学第一附属医院 新疆 乌鲁木齐 830054
- 折叠
摘要
Abstract
Parkinson's disease(PD)is a chronic progressive neurological disease that occurs in middle-aged and elderly individuals,and affects the whole brain.In addition to movement disorders,cognitive impairment(CI)poses a significant challenge for PD patients,profoundly impacting their quality of life.CI has a certain impact on the brain structure,function and metabolism of PD patients,and MRI imaging technology can noninvasively evaluate these changes.Therefore,this article reviewed the research progress of multimodal magnetic resonance imaging techniques such as structural MRI imaging and functional MRI imaging in the changes of brain network structure and function in PD patients with CI(PD-CI),and preliminarily discusses the mechanism of PD-CI,it provided an important basis for clinical diagnosis,treatment and prognosis evaluation,and provided a scientific basis for the formulation of individualized treatment and rehabilitation programs.关键词
帕金森病/认知功能障碍/多模态成像/脑功能/脑微观结构Key words
Parkinson's disease/Cognitive impairment/Multimodal imaging/Brain function/Brain microstructure引用本文复制引用
亚库甫·尔肯,丁爽..MRI多模态成像在帕金森病合并认知功能障碍患者大脑微观结构与功能的研究进展[J].中外医学研究,2025,23(11):180-184,5.
