中医学报（英文）2025，Vol.5Issue(1)：30-34,5.DOI:10.1055/s-0045-1806864
结合现代医学对高凝状态的认识诠释中医血瘀病理机制
Interpretation of the Pathological Mechanism of Blood Stasis in Traditional Chinese Medicine in Light of Understanding of Hypercoagulable States in Modern Medicine
摘要
Abstract
In both Traditional Chinese Medicine(TCM)and modern medicine,they agree that the integrity and healthy structure of the vascular endothelium are essential for normal hemodynamics.Damage to the vascular endothelium can quickly activate the extrinsic coagulation pathway by triggering the tissue factor(TF)and lead to coagulation.This damage,along with a loss of anticoagulant properties through antithrombin Ⅲ(AT Ⅲ),TF pathway inhibitors,and the protein C system,can result in a hypercoagulable state and even thrombosis.Hypercoagulability is not only a common feature of many cancers but also an important factor promoting tumor development and metastasis,which corresponds to the TCM theory of"blood stasis leading to tumors."The pharmacological effects of heparin and aspirin have similarities with TCM's"activating blood circulation and removing blood stasis"theory in improving blood circulation,treating related diseases,and their anti-inflammatory effects.关键词
血瘀/高凝状态/血栓/肝素/阿司匹林/中医/现代医学Key words
blood stasis/hypercoagulable state/thrombosis/heparin/aspirin/Traditional Chinese Medicine/modern medicine引用本文复制引用
陈永..结合现代医学对高凝状态的认识诠释中医血瘀病理机制[J].中医学报（英文）,2025,5(1):30-34,5.基金项目
This work was supported by the Guizhou Provincial Basic Research Program(Natural Science)Youth Guidance Proj-ect {Qian Kehe Foundation-[2024]Youth 307}. （Natural Science）
