中医药学报2025，Vol.53Issue(5)：69-73,5.DOI:10.19664/j.cnki.1002-2392.250099
针灸结合参芪络痹方治疗脑梗死伴颈动脉粥样硬化斑块的临床研究
Clinical Study on Acupuncture and Moxibustion Combined with Shenqi Luobi Formula for the Treatment of Cerebral Infarction with Carotid Artery Atherosclerotic Plaques
摘要
Abstract
Objective:To analyze the clinical efficacy of acupuncture and moxibustion combined with Shenqi Luobi Formula in treating cerebral infarction with carotid artery atherosclerosis(CAS)plaques.Methods:A total of 98 patients with cerebral infarction accompanied by CAS plaques who were admitted to Jiangyin Hospital of Traditional Chinese Medicine from May 2022 to April 2024 were selected.They were randomly divided into two groups:the control group(52 patients),who received acupuncture and moxibustion treatment,and the observation group(46 patients),who received acupuncture and moxibustion combined with Shenqi Luobi Formula.Clinical efficacy,traditional Chinese medicine(TCM)syndrome scores,hemorheological parameters,carotid plaque-related indicators,lipid profile,and adverse reaction rates were compared between the two groups.Results:The TCM syndrome scores and neurological function scores in the observation group were lower than those in the control group(P<0.05).The treatment efficacy rate in the observation group was higher than that in the control group(P<0.05).Hemorheological parameters such as whole blood high shear/low shear viscosity and fibrinogen levels were lower in the observation group(P<0.05).The intima-media thickness(IMT),plaque area,and carotid artery cross-sectional area diameter(CCAD)were lower in the observation group(P<0.05).The incidence of adverse reactions in the observation group was lower than in the control group(P>0.05).After treatment,the observation group showed better lipid profile parameters,including lower levels of low-density lipoprotein cholesterol(LDL-C),higher levels of high-density lipoprotein cholesterol(HDL-C),total cholesterol(TC),and triglycerides(TG)compared to the control group(P<0.05).Conclusion:Acupuncture and moxibustion combined with Shenqi Luobi Formula is effective in treating cerebral infarction with CAS plaques.It can significantly reduce TCM syndrome scores,improve neurological function,lipid profile,hemorheological parameters,and carotid plaque-related indicators.The clinical safety of the treatment is acceptable.关键词
针灸/参芪络痹方/脑梗死/颈动脉粥样硬化斑块Key words
Acupuncture and moxibustion/Shenqi Luobi Formula/Cerebral infarction/Carotid artery atherosclerotic plaques分类
中医学引用本文复制引用
袁鹏,张琬蓉..针灸结合参芪络痹方治疗脑梗死伴颈动脉粥样硬化斑块的临床研究[J].中医药学报,2025,53(5):69-73,5.基金项目
江苏省自然科学青年基金项目(BK20210139) （BK20210139）
