分子影像学杂志2025，Vol.48Issue(5)：633-638,6.DOI:10.12122/j.issn.1674-4500.2025.05.16
酰胺质子转移加权成像与人工智能融合技术在乳腺癌中的应用进展
Application progress of amide proton transfer-weighted imaging and artificial intelligence integration in breast cancer diagnosis
摘要
Abstract
Amide proton transfer-weighted(APTw)imaging,a unique chemical exchange saturation transfer imaging technique,indirectly quantifies the amide proton content in mobile proteins and peptides and pH changes in tissues by detecting the attenuation of free water signals.This provides insights into tissue metabolism,offering rich molecular-level information for the diagnosis and treatment monitoring of breast cancer.In recent years,the integration of APTw imaging with AI has gained attention in breast cancer diagnosis.This review focuses on the applications of APTw imaging combined with AI in differentiating benign and malignant breast lesions,histological grading,analyzing correlations with biomarkers,and evaluating the efficacy of neoadjuvant chemotherapy.It also discusses the challenges and limitations of this technology in practical applications.关键词
酰胺质子转移成像/人工智能/化学交换饱和转移/磁共振成像/乳腺癌Key words
amide proton transfer imaging/artificial intelligence/chemical exchange saturation transfer/magnetic resonance imaging/breast cancer引用本文复制引用
侯琳,林抟宇,陈窕璇,黄海健,黄伟鹏..酰胺质子转移加权成像与人工智能融合技术在乳腺癌中的应用进展[J].分子影像学杂志,2025,48(5):633-638,6.基金项目
广东省医学科研基金立项项目(B2024254) （B2024254）
