摘要
Abstract
Objective Based on the real-world study,to understand the effect of Monascus Capsule on lowering blood lipids,and to provide basis and reference for the prevention and treatment of hyperlipidemia patients.Methods A cross-sectional study was conducted to select 491 patients with hyperlipidemia from 10 regions who took Monascus Capsule from September 1,2023 to September 1,2024.The demographic characteristics,health status and drug use of the patients were collected by self-designed questionnaire.The levels of total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C)and non-high-density lipoprotein cholesterol(Non-HDL-C)were analyzed.At the same time,491 patients were divided into use Monascus Capsule alone group and combined with the statin group according to whether they were combined with statins or not,and the TC,TG,LDL-C,HDL-C and Non-HDL-C levels were compared between the two groups.Results The levels of TC,TG,LDL-C and Non-HDL-C of 491 patients with hyperlipidemia were decreased,while the levels of HDL-C were increased,and the total compliance rate and the compliance rate of each index were increased,with statistical significances(P＜0.05).The mean values of TC decrease(ΔTC),TG decrease(ΔTG),LDL-C decrease(ΔLDL-C)and Non-HDL-C decrease(ΔNon-HDL-C)in different periods of taking Monascus Capsule were positive,and the mean values of HDL-C decrease(ΔHDL-C)were negative overall.Subgroup analysis showed that there were no statistical significances in the levels of TC,TG,LDL-C,HDL-C and Non-HDL-C between the two groups(P＞0.05).Conclusion Monascus Capsule has good effect on lowering blood lipids,which can reduce the levels of TC,TG,LDL-C and Non-HDL-C in patients and increase the level of HDL-C,and the effect of Monascus Capsule on lowering blood lipids is no less than that of statins.关键词
红曲胶囊/高脂血症/降血脂/血脂指标/真实世界研究Key words
Monascus Capsule/Hyperlipidemia/Reduce blood lipid/Blood lipid index/Real-world study分类
临床医学
