国际老年医学杂志2025，Vol.46Issue(3)：308-312,5.DOI:10.3969/j.issn.1674-7593.2025.03.009
瑞马唑仑与丙泊酚对老年腹腔镜手术患者麻醉诱导期血流动力学及术后认知功能的影响
Effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during induction of anesthesia in elderly patients undergoing laparoscopic surgery
摘要
Abstract
Objective To investigate the effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during anesthesia induction in elderly patients undergoing laparoscopic surgery.Methods 116 elderly patients undergoing e-lective laparoscopic surgery in Yibin Hospital,West China Hospital,Sichuan University from December 2022 to March 2024 were se-lected as the study subjects and divided into observation group and control group according to random number table,with 58 cases in each group.Remazolam was used for anesthesia induction and maintenance in the observation group,and Propofol was used for anes-thesia induction and maintenance in the control group.The hemodynamic indicators and the quality of recovery at two different time points were compared,and the occurrence of adverse reactions and cognitive function scores were recorded.Results In the observa-tion group,the heart rate and mean arterial pressure immediately after tracheal intubation and 3 min after intubation were higher than those in the control group(P＜0.05),the spontaneous respiratory recovery time,eye-opening time and extubation time were shorter than those in the control group(P＜0.05),the cognitive function scores at 1 d and 3 d after operation were higher than those in the control group(P＜0.05),the total incidence of adverse reactions was lower than that in the control group(P＜0.05).Conclusion Compared with Propofol,Remazolam is used in elderly laparoscopic surgery,with more stable intraoperative blood flow fluctuations,faster postoperative recovery,and fewer adverse reactions.For patients with less cognitive function,it is suitable for elderly patients with relatively weak body and easily unstable hemodynamics.关键词
瑞马唑仑/丙泊酚/腹腔镜手术/血流动力学/认知功能Key words
Remazolam/Propofol/Laparoscopic surgery/Hemodynamics/Cognitive function引用本文复制引用
邹琪,陈敏,刘京华..瑞马唑仑与丙泊酚对老年腹腔镜手术患者麻醉诱导期血流动力学及术后认知功能的影响[J].国际老年医学杂志,2025,46(3):308-312,5.基金项目
国家自然科学基金资助项目(U20A20394) （U20A20394）
