老年医学与保健2025，Vol.31Issue(2)：317-321,5.
老年男性2型糖尿病患者合并肌少-骨质疏松症相关因素研究
A study on related factors of osteosarcopenia in elderly male patients with type 2 diabetes mellitus
张任飞 1董娟 2李悦芃 2邱蕾2
作者信息
- 1. 北京医院保健医疗部,国家老年医学中心,中国医学科学院老年医学研究院,北京 100730||北京大学第五临床医学院,北京 100730
- 2. 北京医院保健医疗部,国家老年医学中心,中国医学科学院老年医学研究院,北京 100730
- 折叠
摘要
Abstract
Objective To explore potential risk factors for osteosarcopenia(OS)in elderly male patients with type 2 di-abetes mellitus(T2DM).Methods A total of 404 elderly male T2DM patients aged 60 and above who underwent physical examinations in Beijing Hospital from January 2022 to May 2024 were selected.Their baseline information was collected.The dominant hand grip strength,5-time sit-to-stand test,and 6-meter gait speed were measured.Dual-energy X-ray absorptiometry(DXA)was used to determine bone mineral density(BMD)and body composition.Univariate and multivariate Logistic re-gression analyses were performed to identify influencing factors for OS in elderly male T2DM patients.Results The preva-lence of OS among elderly male T2DM patients was 28.96％(117/404).Multivariate Logistic regression analysis showed that higher body mass index(OR=0.902,95％CI:0.775-0.986),increased lowest lumbar bone mineral density(OR=0.000,95％CI:0.000-0.014),and elevated femoral neck bone mineral density(OR=0.001,95％CI;0.000-0.022)were protec-tive factors for OS,while advanced age(OR=1.133,95％CI:1.052-1.257),higher body fat percentage(OR=1.171,95％CI;1.008-1.421),and comorbid chronic obstructive pulmonary disease(OR=1.026,95％CI:1.007-1.052)were risk factors for OS.Conclusion The prevalence of OS is higher in elderly male T2DM patients,and attention should be paid to high-risk populations with higher body fat percentage,lower body mass index,and lower bone mineral density.关键词
老年/男性/2型糖尿病/肌少-骨质疏松症Key words
elderly/male/type 2 diabetes mellitus/osteosarcopenia引用本文复制引用
张任飞,董娟,李悦芃,邱蕾..老年男性2型糖尿病患者合并肌少-骨质疏松症相关因素研究[J].老年医学与保健,2025,31(2):317-321,5.
