检验医学与临床2025，Vol.22Issue(10)：1334-1337,4.DOI:10.3969/j.issn.1672-9455.2025.10.008
纳米碳标记在cN0期甲状腺微小乳头状癌患者颈侧区淋巴结清扫中的应用价值
Application value of carbon nanoparticles labeling in lateral cervical lymph node dissection in patients with cN0 stage papillary thyroid microcarcinoma
摘要
Abstract
Objective To analyze the application value of carbon nanoparticles labeling in lateral cervical lymph node dissection in patients with cN0 papillary thyroid microcarcinoma(PTMC).Methods A total of 95 patients with cN0 PTMC admitted to the First Hospital of Yulin in Shaanxi Province from March 2021 to March 2023 were selected as the research objects,and they were divided into carbon nanoparticles group(47 cases)and control group(48 cases)by random number table method.The control group received surgical treatment.On the basis of the control group,the carbon nanoparticles group was injected with carbon nanopar-ticles suspension before cervical lymph node dissection for thyroid lymph tracing and parathyroid protection.The operation and recovery,the number and metastasis of lateral cervical lymph nodes,the incidence of im-proper parathyroidectomy and complications,and the serum Ca2+and parathyroid hormone(PTH)levels be-fore and 24 h after operation were compared between the two groups.Results The number of lymph node dis-section,the number of lymph node metastasis,and the rate of lymph node metastasis in the nano carbon group were higher than those in the control group,and the rate of improper parathyroidectomy and the incidence of complications were lower than those in the control group,and the differences were statistically significant(P＜0.05).The levels of serum Ca2+and PTH at 24 h after operation in the two groups were lower than those before operation,and the levels of serum Ca2+and PTH at 24 h after operation in the carbon nanoparti-cles group were higher than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Carbon nanoparticles labeling can increase the number of dissected lateral cervical lymph nodes and the resection rate of metastatic lymph nodes without affecting the operation and postoperative recovery,and help to protect the structure and function of the parathyroid gland and reduce the risk of complications.关键词
纳米碳/甲状腺微小乳头状癌/颈侧区淋巴结/淋巴结清扫Key words
carbon nanoparticles/papillary thyroid microcarcinoma/lateral cervical lymph nodes/lymph node dissection分类
医药卫生引用本文复制引用
侯花屏,王孝彬,李庆..纳米碳标记在cN0期甲状腺微小乳头状癌患者颈侧区淋巴结清扫中的应用价值[J].检验医学与临床,2025,22(10):1334-1337,4.基金项目
陕西省重点研发计划项目(2022SF-230). （2022SF-230）
