摘要
Abstract
Objective To analyze the causes of vocal cord adhesion after low-temperature plasma surgery in elderly pa-tients with laryngeal lesions and construct a nomogram prediction model.Methods The clinical data of 214 elderly patients with laryngeal lesions who underwent low-temperature plasma surgery in Department of Throat,Head and Neck Surgery,First Affiliated Hospital of Zhengzhou University were retrospectively collected.Statistical analysis was performed to assess correla-tions between vocal cord adhesion and factors including gender,age,smoking,alcohol consumption,gastroesophageal reflux,lesion type,lesion location,surgical scope,operative time,and postoperative granuloma formation.Logistic regression analy-sis was used to identify independent risk factors for vocal cord adhesion after laryngeal plasma surgery.A nomogram prediction model was established using R language,and its predictive performance was validated by Bootstrap method.Results Among the 214 patients,55 ones developed vocal cord adhesion after surgery.Lesion location,surgical scope and postoperative granu-loma formation were identified as independent risk factors for vocal cord adhesion after laryngeal plasma surgery(P＜0.05).The ROC curve showed that the constructed nomogram had a good discrimination in predicting vocal cord adhesion after laryn-geal plasma surgery(AUC=0.863,95％CI=0.785-0.940).The Bootstrap method was used to verify the nomogram,and the average absolute error of the calibration curve was 0.04,indicating that the calibration curve had a good fit with the ideal curve.Conclusion The lesion location,surgical scope and postoperative granulation formation are independent risk factors for the occurrence of vocal fold adhesion in elderly patients with laryngeal lesions after low-temperature plasma surgery.The con-structed nomogram model based on these factors exhibits strong predictive value for vocal cord adhesion occurrence,and it is helpful to guide the selection of surgical methods and the monitoring of postoperative vocal cord adhesions.关键词
老年/喉部病变/低温等离子/声带粘连/危险因素/预测模型/列线图Key words
elderly/laryngeal lesion/low-temperature plasma/vocal cord adhesions/risk factor/predictive model/no-mogram
