山东中医杂志2025，Vol.44Issue(5)：493-498,6.DOI:10.16295/j.cnki.0257-358x.2025.05.002
基于五脏元真通畅探讨特发性肺纤维化病机与证治
Discussion on Pathogenesis,Syndrome,and Treatment of Idiopathic Pulmonary Fibrosis Based on Unobstructed Flow of Yuanzhen in Five Zang-Organs
摘要
Abstract
Idiopathic pulmonary fibrosis(IPF)belongs to the category of lung atrophy and lung impediment in traditional Chinese medicine.The pathogenesis of IPF is characterized by phlegm and blood stasis obstruction as the superficial manifestation and deficiency of qi and blood as the root cause,which is generally a condition of root deficiency and superficial excess.The Yuanzhen in five-zang organs are mainly composed of qi and blood,transformed by the congenital essence of the kidney,nourished by the acquired qi of water and grains from the spleen and the stomach,circulating through the triple energizer,and flowing throughout the zang-fu organs and meridians of the whole body,exerting functions such as nourishing and moistening,and defending against external pathogenic factors.The characteristics of the lung,which is responsible for dispersion and descent and is rich in qi and blood,are closely related to the unobstructed flow of the Yuanzhen in five-zang organs.Therefore,the treatment of IPF can be based on the unobstructed flow of the Yuanzhen in five-zang organs.In the early stage of IPF,the main pathological change is the disorder of qi movement,and there is no significant depletion or stagnation of the Yuanzhen in five-zang organs.The treatment should focus on eliminating pathogenic factors and protecting the defensive qi.In the middle stage,based on the disorder of qi movement,abnormal blood circulation mainly caused by blood stasis occurs.Although there is stagnation and deficiency of the Yuanzhen in five-zang organs,it is mainly limited to the lung.The treatment should combine both attacking and tonifying methods.In the late stage,due to the long-term disorder of qi and blood circulation,the Yuanzhen in five-zang organs is severely damaged and the flow of the Yuanzhen in five-zang organs is not smooth.The treatment should focus on nourishing and tonifying the Yuanzhen.关键词
特发性肺纤维化/元真通畅/气血/痰瘀痹阻/培补元真Key words
idiopathic pulmonary fibrosis/the unobstructed flow of the Yuanzhen/qi and blood/phlegm and blood stasis obstruction/nourishing and tonifying the Yuanzhen分类
中医学引用本文复制引用
孙誉宵,王晓冬,马鑫来,张伟..基于五脏元真通畅探讨特发性肺纤维化病机与证治[J].山东中医杂志,2025,44(5):493-498,6.基金项目
山东省自然科学基金项目(编号:ZR2021LYZ031) （编号:ZR2021LYZ031）
