神经修复学（英文）2024，Vol.12Issue(2)：87-97,11.DOI:10.1016/j.jnrt.2024.100106
Inhibition of P2X7R alleviates neuroinflammation and brain edema after traumatic brain injury by suppressing the NF-κB/NLRP3 inflammasome pathway
Inhibition of P2X7R alleviates neuroinflammation and brain edema after traumatic brain injury by suppressing the NF-κB/NLRP3 inflammasome pathway
Bingyan Tao 1Jun Zhang 2Jie Pei 3Hao Li 4Guochao Yang 5Xudong Shi 6Zehan Zhang 7Hui Wang 8Zhou Zheng 9Yuyang Liu10
作者信息
- 1. Department of Neurosurgery,The First Medical Centre,Chinese PLA General Hospital,Beijing 100853,China||Department of Neurosurgery,961th Hospital of Joint Logistics Support Force,Qiqihar 161000,Heilongjiang,China||Medical School of Chinese PLA,Beijing 100853,China
- 2. Department of Neurosurgery,The First Medical Centre,Chinese PLA General Hospital,Beijing 100853,China
- 3. Institute of Military Cognition and Brain Sciences,Beijing 100850,China
- 4. Department of Neurobiology,Beijing Institute of Basic Medical Sciences,Beijing 100850,China
- 5. Ministry of Education(MOE)Key Laboratory of Model Animal for Disease Study,Model Animal Research Center,Jiangsu Key Laboratory of Molecular Medicine,Medical School,Nanjing University,Nanjing 210061,Jiangsu,China
- 6. Department of Neurosurgery,The First Medical Centre,Chinese PLA General Hospital,Beijing 100853,China||Medical School of Chinese PLA,Beijing 100853,China
- 7. Department of Neurosurgery,PLA Air Force Hospital of Southern Theatre Command,Guangzhou 510602,Guangdong,China
- 8. Department of Experimental Pathology,Beijing Institute of Radiation Medicine,Beijing 100850,China
- 9. Department of Emergency,920th Hospital of Joint Logistics Support Force,Kunming 650032,Yunnan,China
- 10. Medical School of Chinese PLA,Beijing 100853,China||Department of Neurosurgery,920th Hospital of Joint Logistics Support Force,Kunming 650032,Yunnan,China||Chinese PLA Spinal Cord Injury Treatment Center,Kunming 650032,Yunnan,China
- 折叠
摘要
关键词
Traumatic brain injury/Neuroinflammation/Brain edema/P2X7R/NF-κB/NLRP3Key words
Traumatic brain injury/Neuroinflammation/Brain edema/P2X7R/NF-κB/NLRP3引用本文复制引用
Bingyan Tao,Jun Zhang,Jie Pei,Hao Li,Guochao Yang,Xudong Shi,Zehan Zhang,Hui Wang,Zhou Zheng,Yuyang Liu..Inhibition of P2X7R alleviates neuroinflammation and brain edema after traumatic brain injury by suppressing the NF-κB/NLRP3 inflammasome pathway[J].神经修复学（英文）,2024,12(2):87-97,11.基金项目
This research was funded by the National Natural Science Foundation of China(No.81971167). （No.81971167）
