眼科新进展2025，Vol.45Issue(6)：468-475,8.DOI:10.13389/j.cnki.rao.2025.0082
1990-2021年中国与低、中、高SDI国家40岁以上人群年龄相关性黄斑变性负担趋势比较分析
Comparative analysis of trends in the burden of age-related macular degener-ation in people aged over 40 years in China and low-,middle-,and high-SDI countries from 1990 to 202
摘要
Abstract
Objective To analyze the epidemiological burden of age-related macular degeneration(AMD)in China and low-,middle-,and high-socio-demographic index(SDI)countries,thereby providing a theoretical foundation for the prevention and control of AMD.Methods The data published by Global Burden of Disease(GBD)from 1990 to 2021,in-cluding the number of cases,prevalence,disability-adjusted life years(DALYs),and DALYs rate,were utilized to analyze the characteristics of AMD in China and low-,middle-,and high-SDI countries and assess the burden of AMD and its corre-lation with SDI.Results In 2021,the number of patients with AMD and DALYs in China ranked first in the world.Be-sides,the age-standardized prevalence rate(ASPR)and age-standardized DALYs rate(ASDR)in China ranked 46th and 64th in the world,respectively.The number of patients with AMD and DALYs in high-SDI countries were significantly lower than those in middle-and low-SDI countries.The ASPR and ASDR in China were higher than those in high-SDI countries but lower than those in low-SDI countries,and both exceeded the global averages.The prevalence of AMD among people aged 55 years and above was significantly higher.In high-SDI countries,the highest prevalence of AMD was observed a-mong people aged 80 years or above.The prevalence of AMD in China and middle-SDI countries peaked among people aged 65-69 years;whereas that in low-SDI countries peaked among people aged 75-79 years.The AMD burden in females was significantly higher than that in males.The global number of AMD patients exhibited an increasing trend from 1990 to 2021,with the fastest increase observed in China(3.11-fold).The ASPR in China showed a wave-like increasing trend,while that in low-,middle-,and high-SDI countries showed a decreasing trend during the same period.The overall DALY showed an increasing trend,and the increase in the DALYs in China(2.84-fold)exceeded that in low-,middle-,and high-SDI countries.However,the overall ASDR declined,with the most significant decline observed in high-SDI countries.The AS-DR in China has recently rebounded after a wave-like decline from 1990 to 2021.The analysis results of the slope index of inequality(SII)and concentration index(CI)showed that the gap in the AMD burden between high-income and low-in-come countries widened progressively from 1990 to 2021,with the burden being more severe in low-SDI countries.Conclu-sion In 2021,the number of patients with AMD and DALYs in China ranked first in the world.The overall disease burden of AMD in China was between that of high-and low-SDI countries but was higher than global averages.The prevalence of AMD among people aged 55 years and above was significantly higher,and the burden was higher for females than for males.From 1990 to 2021,the number of patients with AMD and the prevalence of this disease in China exhibited an in-creasing trend,while those in low-,middle-,and high-SDI countries showed a decreasing trend.The overall DALYs in-creased,while the overall ASDR decreased.The gap in the AMD burden between high-income and low-income countries widened,and the burden was more severe in low-SDI countries.It was concluded that the burden of AMD was closely re-lated to age,gender,and SDI,and that its distribution characteristics and trends should be considered in the formulation of prevention and control strategies.关键词
年龄相关性黄斑变性/全球疾病负担/患病率/伤残调整寿命年Key words
age-related macular degeneration/global burden of disease/prevalence/disability-adjusted life years分类
临床医学引用本文复制引用
谷珍珍,陈曦,郝晓凤,谢立科..1990-2021年中国与低、中、高SDI国家40岁以上人群年龄相关性黄斑变性负担趋势比较分析[J].眼科新进展,2025,45(6):468-475,8.基金项目
中国中医科学院眼科医院高水平中医医院揭榜挂帅项目(编号:GSP4-02) （编号:GSP4-02）
中国中医科学院科技创新工程重大攻关项目(编号:CI2021A02606) （编号:CI2021A02606）
卫健委老龄司老年眼健康项目(编号:2023-234) （编号:2023-234）
