眼科新进展2025,Vol.45Issue(6):500-504,5.DOI:10.13389/j.cnki.rao.2025.0088
细胞外囊泡在青光眼治疗中的应用研究进展
Research progress on extracellular vesicles in the treatment of glaucoma
摘要
Abstract
Extracellular vesicles(EVs)are small vesicles secreted by cells,widely present in various body fluids,and they play important biological roles.In recent years,EVs have garnered significant attention as novel diagnostic and thera-peutic tools in multiple ocular diseases.Glaucoma,as a common cause of irreversible blindness,is primarily caused by optic nerve damage associated with pathologically elevated intraocular pressure.Emerging evidence indicates that EVs hold considerable therapeutic potential in glaucoma management,particularly in modulating aqueous humor circulation and pro-viding retinal neuroprotection.This review summarizes the latest research progress on EVs in the treatment of glaucoma.关键词
细胞外囊泡/外泌体/青光眼/房水循环/视网膜神经保护Key words
extracellular vesicle/exosome/glaucoma/aqueous humor circulation/retinal neuroprotection分类
临床医学引用本文复制引用
陈鹏飞,仇紫瑜,刘茜,管怀进,周天球,季敏..细胞外囊泡在青光眼治疗中的应用研究进展[J].眼科新进展,2025,45(6):500-504,5.基金项目
国家自然科学基金(编号:82171038) (编号:82171038)
江苏省卫生健康委科研资助项目(编号:M2021084) (编号:M2021084)
南通市科技项目资助项目(编号:MS22022020) (编号:MS22022020)