现代妇产科进展2025，Vol.34Issue(5)：331-336,6.DOI:10.13283/j.cnki.xdfckjz.2025.05.002
HR-HPV基因整合检测在子宫颈癌筛查应用的中国专家共识
Consensus of Chinese experts on clinical application of HR-HPV gene integration testing in cervical cancer screening
中国优生科学协会阴道镜和宫颈病理学分会 1中华预防医学会肿瘤预防与控制专委会 1中华医学会妇科肿瘤学分会 1中国妇幼健康研究会子宫颈癌防控研究专业委员会 1隋龙 1王临虹 1马丁 1魏丽惠1
作者信息
摘要
Abstract
The incidence and mortality rates of cervical cancer in China are continuously rising,presen-ting a severe challenge for prevention and control.The integration of HR-HPV genes into the human genomic DNA sequence is the key molecular basis for the occurrence of cervical cancer.With the advancement of preci-sion diagnosis and treatment concepts,the rational application of new high-throughput viral integration testing technologies can achieve precise stratification and risk management of HR-HPV positive patients.This expert consensus aims to standardize the application of HR-HPV gene integration testing in cervical cancer screening.Additionally,this consensus will focus on elucidating the role and molecular mechanisms of HR-HPV gene inte-gration in the occurrence and development of cervical cancer,the methods and processes.It will also focus on providing recommendations on HR-HPV gene integration testing for HR-HPV infected individuals,those with ab-normal combined screening results,patients with persistent cervical LSIL(CIN1),treatment and following of cer-vical HSIL(CIN2),and clinical management after treatment of cervical HSIL(CIN2,CIN3).These recommen-dations aim to provide references for clinicians in decision-making for cervical cancer screening management,with the goal of accelerating the elimination of cervical cancer in China.关键词
子宫颈癌/HR-HPV基因整合检测/精准分流/风险分层管理Key words
Cervical cancer/HR-HPV gene integration/Precise triage/Risk stratification management引用本文复制引用
中国优生科学协会阴道镜和宫颈病理学分会,中华预防医学会肿瘤预防与控制专委会,中华医学会妇科肿瘤学分会,中国妇幼健康研究会子宫颈癌防控研究专业委员会,隋龙,王临虹,马丁,魏丽惠..HR-HPV基因整合检测在子宫颈癌筛查应用的中国专家共识[J].现代妇产科进展,2025,34(5):331-336,6.
