中国肺癌杂志2025，Vol.28Issue(4)：304-308,5.DOI:10.3779/j.issn.1009-3419.2025.101.05
肿瘤内微生物群与肺癌关系的研究进展
Research Progress on the Relationship between Intratumor Microbiota and Lung Cancer
摘要
Abstract
Lung cancer has the highest incidence and mortality of any cancer in the world.In recent years,with the development of microbial detection technology,the intratumor microbiota has gradually become a hot spot and frontier in the field of lung cancer research.Studies have found that the microbiota present in tumors can influence the development of lung cancer in a variety of ways.In addition,the intratumor microbiota can be used as a potential biomarker for the diagnosis and prognosis assessment of lung cancer,and the regulation of the intratumor microbiota of lung cancer is expected to become a new type of lung cancer treatment.In this paper,we reviewed the latest research progress on the relationship between intratu-mor microbiota and lung cancer,summarized the origin and characteristics of intratumor microbiota,discussed the mechanism of its influence on the occurrence and development of lung cancer,and explored its potential applications in the diagnosis,treatment and prognosis of lung cancer.关键词
肺肿瘤/瘤内微生物/作用机制/生物标志物Key words
Lung neoplasms/Intratumor microbiota/Mechanism of action/Biomarker引用本文复制引用
朱杨彤,陈佳威,朱燕倩,吴林玉..肿瘤内微生物群与肺癌关系的研究进展[J].中国肺癌杂志,2025,28(4):304-308,5.基金项目
本文受浙江省自然科学基金项目(No.LTGY23H180001)、浙江省卫生健康科技计划项目(No.2022KY230,No.2024KY132)和浙江中医药大学科研项目(No.2022FSYYZY08)资助 This paper was supported by the grants from Zhejiang Provincial Natural Science Foundation of China(No.LT-GY23H180001),Medical Health Science and Technology Project of Zhejiang Provincial Health Commission(No.2022KY230,No.2024KY132)and Research Project of Zhejiang Chinese Medical University(No.2022FSYYZY08)(All to Linyu WU). （No.LTGY23H180001）
