中风与神经疾病杂志2025,Vol.42Issue(5):387-394,8.DOI:10.19845/j.cnki.zfysjjbzz.2025.0075
自身免疫性肌炎治疗进展
Advances in the treatment of autoimmune myositis
摘要
Abstract
Autoimmune myositis(AIM)is a group of autoimmune diseases that primarily affect muscle fibers,often accompanied by the involvement of multiple organs such as the skin,lungs,and joints.It is the most common treatable skel-etal muscle disease in adults.Although most patients with AIM can achieve remission with traditional immunosuppressive therapies,their quality of life can be heavily reduced due to drug-related adverse effects and the high relapse rate and high disability rate of the disease.With the deepening understanding of the immunopathological mechanisms of AIM,various biologics targeting different components of these mechanisms have brought new hope for patients with AIM.This article re-views the advances in the treatment of AIM.关键词
自身免疫性肌炎/间质性肺病/免疫抑制剂/生物制剂/治疗进展Key words
Autoimmune myositis/Interstitial lung disease/Immunosuppressant/Biologics/Treatment advance分类
临床医学引用本文复制引用
赵冰,焉传祝..自身免疫性肌炎治疗进展[J].中风与神经疾病杂志,2025,42(5):387-394,8.基金项目
国家自然科学基金面上项目(82071412) (82071412)
青岛市自然科学基金青年项目(24-4-4zrjj-104-jch) (24-4-4zrjj-104-jch)
青岛市神经系统罕见病临床医学研究中心(22-3-7-lczx-3-nsh) (22-3-7-lczx-3-nsh)